Endoscopic Cyclophotocoagulation (ECP) is a glaucoma surgery designed to reduce the intraocular pressure (IOP) by partially ablating the ciliary processes to decrease aqueous humour production and secretion. The aim of this paper is to review the literature regarding the background, indications and results of the surgery. Although there are case reports of visually devastating complications, including persistent hypotony and phthisis, the use of ECP is often reported in eyes with advanced diseases. When compared with both trabeculectomy and aqueous shunt implantation, the visual outcomes were better with ECP while the IOP outcomes were very similar. The evidence supports ECP as a very effective surgical option in recalcitrant glaucoma while some evidence supports its safety for use as a primary procedure.

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http://dx.doi.org/10.1111/aos.12529DOI Listing

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Article Synopsis
  • * Endoscopic cyclophotocoagulation (ECP) is a key treatment method that works by reducing the production of aqueous humor through the coagulation of the ciliary body, and has been in use since the 1990s.
  • * The review discusses the technology used in ECP, its effectiveness compared to other treatments, its current clinical use, possible postoperative complications, and how ECP’s role in glaucoma treatment is expected to grow and adapt with new advancements.
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Article Synopsis
  • A 69-year-old Japanese woman with severe glaucoma and a history of multiple eye surgeries experienced corneal endothelial graft failure after having endoscopic cyclophotocoagulation (ECP) to manage high intraocular pressure (IOP).
  • She underwent two DSAEK procedures, with the second one initially successful but ultimately leading to graft failure after subsequent ECP treatment.
  • The case highlights the need for careful decision-making regarding ECP in patients with existing corneal endothelial issues.
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Purpose: The Hydrus microstent was approved by the FDA in August 2018 for use with cataract surgery to reduce IOP in patients with mild to moderate primary open angle glaucoma (POAG). Pivotal clinical trials demonstrated its overall safety and efficacy in lowering IOP. However, malpositioning of the implant can result in uveitis-glaucoma-hyphema (UGH) syndrome necessitating device explantation.

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Long-term efficacy and safety of posterior endoscopic cyclophotocoagulation in refractory glaucoma: A 5-year follow-up study at a tertiary eye center.

Asia Pac J Ophthalmol (Phila)

June 2024

Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Sciences Key Lab, Beijing 100730, China. Electronic address:

Purpose: To evaluate the long-term efficacy of endoscopic cyclophotocoagulation (ECP) via a pars plana approach in a large cohort of refractory glaucoma patients DESIGN: Single-center, retrospective, longitudinal, cohort study.

Methods: This study recruited patients who underwent ECP and consecutively visited and were followed up for at least 5 years at Beijing Tongren Eye Center, China from January 2013 to December 2017. All patients underwent a complete ophthalmic examination.

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Age is an important risk factor for both glaucoma and cataract. As global life expectancy continues to rise, the prevalence of concomitant open-angle glaucoma (OAG) and cataracts is increasing. Currently, there is a lack of definitive consensus on the optimal management approach for such individuals.

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