We develop a semirelativistic quantum fluid theory based on the expansion of the Dirac Hamiltonian to second order in 1/c. By making use of the Madelung representation of the wave function, we derive a set of hydrodynamic equations that comprises a continuity equation, an Euler equation for the mean velocity, and an evolution equation for the electron spin density. This hydrodynamic model is then applied to study the dynamics of a dense and weakly relativistic electron plasma. In particular, we investigate the impact of the quantum-relativistic spin effects on the Faraday rotation in a one-dimensional plasma slab irradiated by an x-ray laser source.
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http://dx.doi.org/10.1103/PhysRevE.90.013103 | DOI Listing |
ACS Appl Mater Interfaces
January 2025
State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, College of Biological Science and Medical Engineering, Donghua University, Shanghai 201620, China.
To simplify the composition and improve the efficacy of metal-phenolic network (MPN)-based nanomedicine, herein, we designed an MPN platform to deliver programmed death ligand-1 (PD-L1) antibody (anti-PD-L1) for combined tumor chemo/chemodynamic/immune therapy. Here, generation 5 poly(amidoamine) dendrimers conjugated with gossypol (Gos) through boronic ester bonds were used as a synthetic polyphenol to coordinate Mn, and then complexed with anti-PD-L1 to obtain the nanocomplexes (for short, DPGMA). The prepared DPGMA exhibited good water dispersibility with a hydrodynamic size of 166.
View Article and Find Full Text PDFJ Hepatol
January 2025
Department of Surgery, Sir Y.K. Pao Centre for Cancer, The Chinese University of Hong Kong, Shatin, Hong Kong, China. Electronic address:
Background & Aims: The ubiquitin receptor ADRM1/Rpn13 governs the specificity of eukaryotic protein degradation. By SMRT sequencing, we first discovered a novel spliced variant of ADRM1 with a skipped exon 9, termed ADRM1-ΔEx9, in human hepatocellular carcinoma (HCC). This study aimed to elucidate this novel ubiquitin receptor's underlying biology and clinical implications in HCC.
View Article and Find Full Text PDFJ Hepatol
January 2025
Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China; Clinical Medical Research Center of Hepatic Surgery at Hubei Province, Wuhan 430030, China; Hubei Key Laboratory of Hepato-Pancreato-Biliary Diseases, Wuhan 430030, China; Key Laboratory of Organ Transplantation, Ministry of Education, NHC Key Laboratory of Organ Transplantation, , Chinese Academy of Medical Sciences, Wuhan 430030, China. Electronic address:
Background & Aims: Hepatocellular carcinoma (HCC) is an aggressive malignancy with few effective treatment options. H3Q5ser, a serotonin-based histone modification mediated by transglutaminase 2 (TGM2), affects diverse biological processes, such as neurodevelopment. The role of TGM2-mediated H3Q5ser in HCC progression remains unclear.
View Article and Find Full Text PDFMar Pollut Bull
January 2025
Ecology & Environment Research Group, Centre for Water Resources Development and Management, Kozhikode, India.
This study evaluates the influence of water current and suspended sediment concentration (SSC) on microplastic distribution in various mixing regimes of the Ashtamudi estuary, India. Microplastic abundance ranged from 3.2 to 53 items/L, with highest concentrations observed near the confluence of the river and the sea.
View Article and Find Full Text PDFBackground: The spinal intrathecal space, characterized by a complex three-dimensional (3D) fluid-filled geometry with varying levels of anatomic intricacy, plays a pivotal role in drug administration strategies targeting the central nervous system (CNS). Lumbar injections into this space represent a clinically used approach for delivering therapeutics directly to the brain, bypassing critical barriers such as the blood-brain and blood-cerebrospinal fluid barriers. A nuanced understanding of CSF dynamics is vital for comprehending physiological states of the CNS for drug delivery.
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