AI Article Synopsis
- The study aimed to observe wound healing after corneal stromal thinning using anterior segment optical coherence tomography (AS-OCT) and slit lamp observations.
- Four patients with corneal stromal thinning were monitored through serial AS-OCT and slit-lamp exams to track the healing process and measure corneal thickness.
- Findings showed that AS-OCT effectively detected changes like epithelial hypertrophy, scar tissue formation, and differences in corneal thickness during healing, indicating it's a valuable tool for assessing corneal wounds.
Article Abstract
Purpose: The aim of this study was to observe the wound healing process after corneal stromal thinning by using anterior segment optical coherence tomography (AS-OCT) and a slit lamp.
Methods: Four patients with corneal stromal thinning (2 patients: corneal iron foreign bodies; 2 patients: keratitis) were included. Serial AS-OCT and slit-lamp examinations were used to follow up the progress of these patients. The thicknesses of the whole cornea and the corneal stroma were measured with AS-OCT and compared with the findings observed during the slit-lamp examination.
Results: AS-OCT showed that epithelial hypertrophy and hyperplasia initially occurred in the area of the corneal stromal thinning; subsequently, scar tissue formed in the area with an improvement in the thickness of the corneal stroma. This wound healing process was observed in all 4 patients. The scar tissue initially appeared opaque on slit-lamp examination and was characterized by a high signal produced on AS-OCT, which was different from the normal corneal stroma. The scar tissue gradually appeared clear on slit-lamp examination; however, the high signal on AS-OCT remained.
Conclusions: AS-OCT can be used to detect the wound healing process of corneal stromal thinning.
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| http://dx.doi.org/10.1097/ICO.0000000000000223 | DOI Listing |
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