Adenosarcoma of the uterine body is a rare mixed tumor in which a benign epithelial component is mixed with a malignant stromal element. It has been considered that this tumor originates from the endometrium and its most common finding of imaging is a polypoid tumor occupying the uterine cavity. The authors herein present a case of 37-year-old female with a complaint of abnormal vaginal bleeding. At the first visit, transvaginal ultrasound and magnetic resonance imaging (MRI) showed a round mass with a diameter of one cm in the uterine wall. No malignant pathological finding was detected. The patient visited the authors again one year later, because of continuous bleeding. At that time, they found a polypoid tumor in the uterine cavity, which turned out to be adenosarcoma with sarcomatous overgrowth. The round mass in the uterus detected at first time seems to have been incipience of adenosarcoma. Prodromal sign of adenosarcoma has not been reported previously.
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Int Med Case Rep J
January 2025
Qingdao Central Hospital, University of Health and Rehabilitation Sciences, Qingdao, Shandong, People's Republic of China.
In this case, the patient had uterine adenocarcinoma with a huge necrotic mass prolapsed from the vagina, complicated by necrotic infection and massive bleeding. Based on ultrasound results preoperatively, uterine prolapse with infected necrosis was considered due to significant vaginal bleeding, prompting emergency surgery and blood transfusion. Postoperatively, pathology review indicated a misdiagnosis.
View Article and Find Full Text PDFInt J Gynecol Pathol
December 2024
Department of Pathology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, P.R. China.
The incidence of neurotrophic tyrosine kinase receptor (NTRK) fusion uterine sarcoma is extremely low, and reports have been mostly focused on cases localized to the cervix. So far, only 4 cases have been reported of the uterine corpus. In this study, we reported a case of NTRK fusion corpus sarcoma.
View Article and Find Full Text PDFAbdom Radiol (NY)
December 2024
Department of Radiology, The Jikei University School of Medicine, Tokyo, Japan.
Objectives: To comprehensively summarize the characteristics of magnetic resonance imaging (MRI) findings of uterine adenosarcoma through a systematic review and case series analysis.
Methods: A literature search was conducted in MEDLINE, Scopus, and Embase databases on June 3, 2024. In total, 25 cases from 23 articles were selected, and five cases from the authors' institution were included.
J Obstet Gynaecol Res
January 2025
Department of Obstetrics and Gynecology, Nihon University School of Medicine, Tokyo, Japan.
Aim: To provide information including the trend of gynecological malignancies in Japan, we hereby present the Annual Patient Report for 2021 and the Annual Treatment Report for 2016, on the outcomes of patients who started treatment in 2016.
Methods: The Japan Society of Obstetrics and Gynecology maintains an annual tumor registry, where information on gynecological malignancies from various participating institutions is gathered. The data of patients whose treatment with gynecologic malignancies was initiated in 2021 were analyzed retrospectively.
Sci Prog
November 2024
Department of Pathology, Guiqian International General Hospital, Guiyang, Guizhou Province, China.
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