We present a preliminary test of the Ensemble Optimal Statistical Interpolation (EnOSI) method for the statistical tracking of an emerging epidemic, with a comparison to its popular relative for Bayesian data assimilation, the Ensemble Kalman Filter (EnKF). The spatial data for this test was generated by a spatial susceptible-infectious-removed (S-I-R) epidemic model of an airborne infectious disease. Both tracking methods in this test employed Poisson rather than Gaussian noise, so as to handle epidemic data more accurately. The EnOSI and EnKF tracking methods worked well on the main body of the simulated spatial epidemic, but the EnOSI was able to detect and track a distant secondary focus of infection that the EnKF missed entirely.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143132 | PMC |
| http://dx.doi.org/10.1016/j.sste.2014.06.004 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Pre-to-post COVID-19 pandemic trends in time from emergency department arrival to inpatient floor arrival: Door to floor time.
Am J Emerg Med
December 2024
Department of Internal Medicine (Section of General Internal Medicine, Program for Hospital Medicine), Yale University School of Medicine, New Haven, CT, USA; Department of Pediatrics (Section of Hospital Medicine), Yale University School of Medicine, New Haven, CT, USA.
Boarding of admitted patients in the Emergency Department (ED) changes both the setting and teams providing care during the initial phase of admissions. We measured the waiting time from ED door arrival to inpatient floor arrival for 17,944 admissions to internal medicine services over a 5-year period from 2018 to 2023 and propose this as a metric for the total delay in care associated with ED boarding, termed "Door to Floor" (DTF) time. We find a sustained increase as well as significant seasonal and day-of-the-week variation in DTF times.
View Article and Find Full Text PDFRole of PCBP2 in regulating nanovesicles loaded with curcumin to mitigate neuroferroptosis in neural damage caused by heat stroke.
J Nanobiotechnology
December 2024
Key Laboratory of Special Environmental Medicine of Xinjiang, General Hospital of Xinjiang Military Command, No. 359, Youhao North Road, Urumqi, Xinjiang, China.
Objective: This study aims to elucidate the mechanisms by which nanovesicles (NVs) transport curcumin(CUR) across the blood-brain barrier to treat hypothalamic neural damage induced by heat stroke by regulating the expression of poly(c)-binding protein 2 (PCBP2).
Methods: Initially, NVs were prepared from macrophages using a continuous extrusion method. Subsequently, CUR was loaded into NVs using sonication, yielding engineered cell membrane Nanovesicles loaded with curcumin (NVs-CUR), which were characterized and subjected to in vitro and in vivo tracking analysis.
A robust MPPT framework based on GWO-ANFIS controller for grid-tied EV charging stations.
Sci Rep
December 2024
Division of Sustainable Development, College of Science and Engineering, Hamad Bin Khalifa University, Qatar Foundation, Doha, Qatar.
As electric vehicles gain popularity, there has been a lot of interest in supporting their continued development with the aim of enhancing their dependability, environmental advantages, and charging efficiency. The scheduling of navigation and charging for electric vehicles is among the most well-known research topics. For optimal navigation and charging scheduling, the coupled network state between the transportation and power networks must be met; moreover, the scheduling outcomes might significantly impact these networks.
View Article and Find Full Text PDFAperiodic spectral slope tracks the effects of brain state on saliency responses in the human auditory cortex.
Sci Rep
December 2024
Department of Neurosurgery, Baylor College of Medicine, Houston, USA.
Alteration of responses to salient stimuli occurs in a wide range of brain disorders and may be rooted in pathophysiological brain state dynamics. Specifically, tonic and phasic modes of activity in the reticular activating system (RAS) influence, and are influenced by, salient stimuli, respectively. The RAS influences the spectral characteristics of activity in the neocortex, shifting the balance between low- and high-frequency fluctuations.
View Article and Find Full Text PDFUsing T-Cell Subsets to Better Characterize Immunoresiliency and Immunodeficiency in Patients with Recurrent Infections.
Infect Dis Rep
December 2024
Department of Medicine, University of Wisconsin-Madison, Madison, WI 53706, USA.
Background/objectives: Common Variable Immunodeficiency Disease (CVID) and other immunodeficiencies can present in subtle and variable ways. Whether or not a genetic lesion can be identified, there are not well understood biomarkers that quantitatively describe how severe a deficiency is. Here we discuss two possible ranking systems, CD4/CD8 T cell ratios and Immune Health Grades, and how such data maybe applicable to some immunodeficiencies.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!