Background: Early detection of basal cell carcinoma (BCC) is of crucial importance, as serious morbidity may result from undiagnosed tumor.
Objective: To evaluate diagnostic significance (specificity, sensitivity, positive and negative predictive value) of dermoscopic features in BCCs.
Methods: A prospective observational study was conducted using contact polarized dermoscopy to evaluate the presence of various dermoscopic features. Images were evaluated for a range of dermoscopic colors, structures, and vessels.
Setting: Specialized University Clinic.
Patients: A sample of 151 histopathologically verified BCCs was collected from 116 patients (64 males and 52 females). The populations included predominantly Caucasian individuals.
Main Outcome Measures: The sensitivity, specificity, positive and negative predictive values of the various dermoscopic features seen in BCCs were calculated according to standard formulas.
Results: The highest diagnostic value (specificity [Sp] = 100%, positive predictive value [PPV] = 100%) for BCC had spoke-wheel areas, short fine telangiectasias, white rosette, annular hypopigmentation, multiple erosions, and ulceration. Arborizing vessels (Sp = 96%, PPV = 98%) and microvessels (Sp = 93%, PPV = 97%) had significant diagnostic value for BCC. Annular distribution of telangiectatic vessels (Sp = 96%), translucency (Sp = 93%), and multiple blue-gray globules (Sp = 89%) had the same PPV of 95% for BCCs. Other dermoscopic features of this study are not strongly associated with the diagnosis of BCC.
Conclusion: Dermoscopic features relevant for diagnosis of BCC have different diagnostic "weight." Clinicians should have known the sensitivity and specificity of each relevant feature before they can make an accurate dermoscopic diagnosis of BCC.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/dsu.0000000000000031 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Lichen nitidus.
Clin Exp Dermatol
January 2025
Department of Dermatology, Venereology and Leprosy, Sri Manakula Vinayagar Medical College and Hospital, Pondicherry, India.
Article Synopsis
- Lichen nitidus (LN) is a rare skin condition that causes small, shiny, flat-topped bumps mainly in children and young adults, with its cause still unclear but likely linked to immune responses.
- The condition is typically asymptomatic and appears on areas like the trunk, upper limbs, and genitals, with diagnosis often based on a specific histological pattern.
- While LN usually resolves on its own, some cases may persist and require topical treatments, and this review provides insights into its clinical features and management strategies for dermatologists.
Dermoscopy of Basal Cell Carcinoma Part 2: Dermoscopic Findings by Lesion Subtype, Location, Age of Onset, Size and Patient Phototype.
Cancers (Basel)
January 2025
Department of Dermatology, Institute of Medical Sciences, Medical College, Rzeszow University, 35-310 Rzeszow, Poland.
Basal cell carcinoma (BCC) is the most prevalent type of skin cancer worldwide. Despite its low metastatic potential, certain subtypes present an aggressive clinical course. Part II focuses on the different dermoscopic patterns observed in BCC, depending on the lesion subtype, its location on the body, the patient's age, the size of the tumor, and skin phototype.
View Article and Find Full Text PDFA Window into the Vascular Endothelium in Covid-19: Nails.
Dermatol Pract Concept
January 2025
Pamukkale University Faculty of Medicine, Department of Dermatology, Denizli, Turkey.
Introduction: Endothelial damage is associated with acute and long-term coronavirus disease 2019 (COVID-19) complications. Proximal nailfold capillaries and nail beds give important clues to microvascular changes associated with endothelial dysfunction.
Objective: We aimed to use dermoscopy to examine the proximal nailfold capillaries and nail bed of COVID-19 patients and identify microvascular changes.
Ultraviolet-Induced Fluorescence Dermoscopy, a Novel Diagnostic Technique in Dermatological Practice: A Systematic Review.
Indian Dermatol Online J
December 2024
Department of Experimental and Clinical Medicine, DISM, Institute of Dermatology Udine, Udine, Italy.
Introduction: Ultraviolet-induced fluorescence dermoscopy (UVF dermoscopy) is a novel diagnostic technique for identifying and diagnosing numerous skin tumors, inflammatory dermatoses, and infectious diseases. The ultraviolet (UV) band has a wavelength ranging from 10 to 400 nm. When intense UV radiation with shorter wavelengths strikes a target chromophore, visible light (VL) with a longer wavelength and lower energy is produced in the skin.
View Article and Find Full Text PDFDermoscopic Features of Diaper Dermatoses in Children: A Descriptive Pilot Study.
Indian Dermatol Online J
November 2024
Department of Dermatology, Venereology, and Leprosy, Gandhi Medical College, Secundarabad, Telangana, India.
Background: Diaper dermatoses broadly refer to skin disorders that occur in the diaper area. Dermoscopy is a non-invasive diagnostic tool that magnifies subsurface structures of the skin that are invisible to the unaided eye.
Aim: To identify and describe the dermoscopic features of dermatoses in the diaper area.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!