AI Article Synopsis

  • The cerebellum is crucial for movement coordination and is also linked to mood, cognition, and psychiatric disorders.
  • Dandy Walker Malformation involves underdevelopment of the cerebellar vermis and can exist in a variant form when the posterior fossa size is normal.
  • A case study of a 32-year-old male with a 12-year history of Bipolar I Disorder revealed manic and depressive symptoms, with MRI findings indicating features consistent with Dandy Walker Variant.

Article Abstract

Cerebellum is known to play an important role in coordination and motor functions. In some resent studies it is also considered to be involved in modulation of mood, cognition and psychiatric disorders. Dandy Walker Malformation is a congenital malformation that is characterized by hypoplasia or aplasia of the cerebellar vermis, cystic dilatation of the fourth ventricle and enlargement of the posterior fossa. When the volume of posterior fossa is normal, the malformation is called Dandy Walker Variant. Case is a 32 year old male with a 12 year history of Bipolar I Disorder presented with manic and depresive symptoms, including dysphoric and depressive affect, anhedonia, suicidal thoughts and behaviours, thoughts of fear about future, overtalkativeness and graphomania, increased energy, irregular sleep, loss of appetite, increased immersion in projects, irritability, agressive behavior, impulsivity. Cranial Magnetic Resonance Imaging was compatible to the morphological features of Dandy Walker Variant.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124195PMC
http://dx.doi.org/10.4306/pi.2014.11.3.336DOI Listing

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