We describe a patient with markedly elevated lipoprotein(a) (Lp(a)) without any other lipid abnormalities. After a myocardial infarction, she was treated with combination of extended-release niacin and statin. An 88% reduction in Lp(a) was observed during 5 years of treatment, which is much better response than usually reported.
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http://dx.doi.org/10.1016/j.jacl.2014.03.006 | DOI Listing |
Sci Rep
January 2025
Mallinckrodt Institute of Radiology, Washington University School of Medicine, 4515 McKinley Ave., St. Louis, MO, 63110, USA.
Functional magnetic resonance imaging (fMRI) has dramatically advanced non-invasive human brain mapping and decoding. Functional near-infrared spectroscopy (fNIRS) and high-density diffuse optical tomography (HD-DOT) non-invasively measure blood oxygen fluctuations related to brain activity, like fMRI, at the brain surface, using more-lightweight equipment that circumvents ergonomic and logistical limitations of fMRI. HD-DOT grids have smaller inter-optode spacing (~ 13 mm) than sparse fNIRS (~ 30 mm) and therefore provide higher image quality, with spatial resolution ~ 1/2 that of fMRI, when using the several source-detector distances (13-40 mm) afforded by the HD-DOT grid.
View Article and Find Full Text PDFJ Reprod Immunol
January 2025
Chengdu Fifth People's Hospital, (School of Medical and Life Sciences/Affiliated Fifth People's Hospital, Chengdu University of Traditional Chinese Medicine), Chengdu, China. Electronic address:
The endometrial and vaginal microbiota have co-evolved with the reproductive tract and play a key role in both health and disease. However, the difference between endometrial and vaginal microbiota, as well as their association with reproductive outcomes in women undergoing frozen embryo transfer, remains unclear. 120 women who underwent in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) and whole embryo freezing were enrolled.
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
College of Biosystems Engineering and Food Science, National-Local Joint Engineering Laboratory of Intelligent Food Technology and Equipment, Zhejiang Key Laboratory for Agro-Food Processing, Integrated Research Base of Southern Fruit and Vegetable Preservation Technology, Fuli Institute of Food Science, Zhejiang University, Hangzhou 310058, China; Innovation Center of Yangtze River Delta, Zhejiang University, Jiaxing 314102, China. Electronic address:
Starch-ferulic acid (FA) composites have been developed for medical and food fields, while little focus is caused on their use in functional products by 3D printing. In this work, dynamic high-pressure microfluidization was employed to treat starch at various concentrations, for preparing modified starch-FA composites. The high-performance liquid chromatography results showed that an increased starch concentration was conducive to a high yield of composite with enhanced binding of FA.
View Article and Find Full Text PDFPLoS One
January 2025
Insilicogen, Inc., Yongin, Republic of Korea.
With the development of the Korean economy, demand for high-quality beef, specifically Hanwoo beef, is escalating, with marbling traits-measured by the widely used marbling score-being a key contributor to meat palatability. The differences between the high-quality and the lower-quality meat, according to the satisfaction of the customers, are not the result from only the degree of marbling but also from the delicacy of the marbling flecks distribution. Using the computer marbling analysis technique, an index for quantifying marbling fineness of 256 sirloin cuts at 12th- 13th thoracic vertebra named F7 index was developed in this study.
View Article and Find Full Text PDFPLoS One
January 2025
College of Geography and Environmental Science, Guizhou Normal University, Guiyang, China.
It is significant to research the ecological risk of land use landscape to promote ecological conservation and restoration. The characteristics of land use dynamic change in Baili Rhododendron National Forest Park were analyzed based on GlobeLand30 data for three periods in 2000, 2010 and 2020. With the support of the landscape ecological risk evaluation model and spatial analysis methods, the features of spatial and temporal differentiation of ecological risk and its spatial correlation in the study area were evaluated.
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