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Clostridium difficile: improving the prevention paradigm in healthcare settings. | LitMetric

Clostridium difficile: improving the prevention paradigm in healthcare settings.

Expert Rev Anti Infect Ther

Department of Infection Prevention, Providence Saint John's Health Center, 2121 Santa Monica Blvd, Santa Monica, CA 90404, USA.

Published: September 2014

Clostridium difficile infection (CDI) is a major public health problem worldwide with significant morbidity and mortality that is spread by spores and fecal oral transmission. A variety of risk factors have been identified. Some risk factors such as age, are not amenable to change, while others such as antimicrobial utilization have resulted in broadly implemented antimicrobial stewardship programs. New risk factors are emerging such as proton pump inhibitor (PPI) use, irritable bowel disease (IBD) and obesity, with others yet to be determined. Prevention of spread of CDI is imperative, since therapy remains imperfect. We review established and emerging risks for CDI and offer potential preventative strategies with the use of a multidisciplinary CDI prevention bundle checklist.

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Source
http://dx.doi.org/10.1586/14787210.2014.942284DOI Listing

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