The method of extracorporeal CO2 elimination (ECCO2-R) as described by Luiciano Gattinoni and Theodor Kolobow is compared with earlier extra corporeal methods such as extracorporeal membrane oxygenation. The physiological fundamentals of the method, as well as indications and contraindications are explained. - The results of more than 100 patients treated worldwide are discussed together with the present problems of the method. In cases of severe ARDS stage IV, ECCO2-R definitely reduces mortality.
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Front Transplant
January 2025
Department of Surgical, Medical, Biomolecular Pathology and Intensive Care, University of Pisa, Pisa, Italy.
Background And Aims: There is growing interest in the environmental impact of surgical procedures, yet more information is needed specifically regarding liver transplantation. This study aims to quantify the total greenhouse gas emissions, or carbon footprint, associated with adult whole-size liver transplantation from donors after brain death, including the relevant back-table graft preparation.
Methods: The carbon footprint was calculated retrospectively using a bottom-up approach.
J Clin Med
December 2024
Department of Adult Critical Care, Guy's and St Thomas' NHS Foundation Trust, King's Health Partners, London SE1 9RT, UK.
Extracorporeal carbon dioxide removal (ECCOR) is an emerging technique designed to reduce carbon dioxide (CO) levels in venous blood while enabling lung-protective ventilation or alleviating the work of breathing. Unlike high-flow extracorporeal membrane oxygenation (ECMO), ECCOR operates at lower blood flows (0.4-1.
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December 2024
Department of Critical Care, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
Rationale: The impact of extracorporeal carbon dioxide removal (ECCOR) on work of breathing and aeration in exacerbations of chronic obstructive pulmonary disease (AECOPD) is poorly understood.
Objectives: The study explores the impact of non-invasive ventilation (NIV) and ECCOR on respiratory drive, effort and distribution of ventilation in AECOPD.
Methods: Patients enrolled in a randomised controlled study of the addition of ECCOR to NIV compared with NIV underwent oesophageal pressure measurement, electrical impedance tomography and parasternal electromyography.
J Trauma Acute Care Surg
December 2024
From the Autonomous Reanimation and Evacuation Research Program (A.I.B., T.R.R., B.M.B., D.S.W.), The Geneva Foundation, San Antonio; US Army Institute of Surgical Research (B.S.J., C.N., L.C.C.), Joint Base San Antonio-Fort Sam Houston, Texas; Division of Traumatology, Surgical Critical Care and Emergency Surgery (J.W.C.), Penn Presbyterian Medical Center, Philadelphia, Pennsylvania; Seastar Medical (K.K.C.), Denver, Colorado; and Division of Trauma and Emergency Surgery (L.C.C.), University of Texas San Antonio, San Antonio, Texas.
Background: Awareness of ventilator-induced lung injury contributed to increased use of extracorporeal interventions, but not immediately after injury, before acute respiratory distress syndrome (ARDS) ensues. Our objective was to evaluate the role of venovenous extracorporeal carbon dioxide removal (ECCO2R) in management of mechanically ventilated swine with smoke inhalation injury and 40% body surface area burns.
Methods: Yorkshire swine (n = 29, 43.
Perfusion
November 2024
Perfusion Department, Great Ormond Street Hospital, London, UK.
Introduction: This study aimed to identify characteristics associated with survival during and post Extra Corporeal Membrane Oxygenation (ECMO) therapy, in patients with acute respiratory distress syndrome (ARDS) during the COVID-19 pandemic.
Methods: A retrospective observational study on 94 consecutive patients with confirmed COVID-19 induced ARDS supported by ECMO was carried out 49/94 (52.7%) patients survived to hospital discharge.
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