Background: Concerns have been raised about the possibility of a predisposition of Kawasaki disease (KD) to abnormal lipid profile after an acute phase of disease, which can predispose them to premature atherosclerosis later in life. We determined the lipid profile of children late after KD, and compared it with controls.

Methods: This historical cohort was conducted on 32 subjects: 16 children with history of uncomplicated KD (age 11.8 ± 3.3 years, interval from the initial episode 7.1 years), and 16 healthy age-matched of their sibling or cousins. Fasting serum total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and triglycerides (TG) levels were compared between groups. In addition, blood pressure and body mass index (BMI) were measured and compared.

Results: Six out of 16 KD patients and 7 out of 16 controls had abnormal lipid values. No significant difference was found in mean values of systolic blood pressures, diastolic blood pressures, BMI, TG, TC, HDL-C, and LDL-C between cases and controls.

Conclusions: We conclude that although Iranian KD children probably had no different lipid profile compared with controls, but due to finding dyslipidemia in more than one-third of KD subjects, we suggest that periodic control of lipid values in these patients is of crucial importance.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124558PMC

Publication Analysis

Top Keywords

lipid profile
16
kawasaki disease
8
iranian children
8
abnormal lipid
8
lipoprotein cholesterol
8
lipid values
8
blood pressures
8
lipid
5
report lipid
4
profile
4

Similar Publications

Background: The authors aimed to explore the association of fatty acids with periodontitis and its severity and to assess causality using Mendelian randomization (MR) analyses.

Methods: Data for participants with complete data were extracted from the 2009-2014 National Health and Nutrition Examination Survey. Weighted logistic regression was used to explore the relationship between dietary fatty acids and periodontitis and its severity.

View Article and Find Full Text PDF

The developmental lipidome of Nippostrongylus brasiliensis.

Parasit Vectors

January 2025

Department of Veterinary Biosciences, Melbourne Veterinary School, Faculty of Science, The University of Melbourne, Parkville, VIC, 3010, Australia.

Background: Nippostrongylus brasiliensis-a nematode of rodents-is commonly used as a model to study the immunobiology of parasitic nematodes. It is a member of the Strongylida-a large order of socioeconomically important parasitic nematodes of animals. Lipids are known to play essential roles in nematode biology, influencing cellular membranes, energy storage and/or signalling.

View Article and Find Full Text PDF

This study investigated the effects of non-thermal atmospheric plasma (NTAP) treatment on the growth, chemical composition, and biological activity of geranium (Pelargonium graveolens L'Herit) leaves. NTAP was applied at a frequency of 13.56 MHz, exposure time of 15 s, discharge temperature of 25 °C, and power levels (T1 = 50, T2 = 80, and T3 = 120 W).

View Article and Find Full Text PDF

Background: Gestational exposure to non-persistent endocrine-disrupting chemicals (EDCs) may be associated with adverse pregnancy outcomes. While many EDCs affect the endocrine system, their effects on endocrine-related metabolic pathways remain unclear. This study aims to explore the global metabolome changes associated with EDC biomarkers at delivery.

View Article and Find Full Text PDF

Background: Cardiovascular risk factors (CRFs) like hypertension, high cholesterol, and diabetes mellitus are increasingly linked to cognitive decline and dementia, especially in cerebral small vessel disease (cSVD). White matter hyperintensities (WMH) are closely associated with cognitive impairment, but the mechanisms behind their development remain unclear. Blood-brain barrier (BBB) dysfunction may be a key factor, particularly in cSVD.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!