A highly chemo- and stereoselective cobalt-catalyzed hydroarylative cyclization of 1,6-enynes with aromatic ketones and esters to synthesize functionalized pyrrolidines and dihydrofurans is described. A mechanism involving cobaltacycle triggered C-H activation of aromatic ketones and esters was proposed.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/ol501904e | DOI Listing |
Publication Analysis
Top Keywords
aromatic ketones
12
ketones esters
12
cobalt-catalyzed hydroarylative
8
hydroarylative cyclization
8
cyclization 16-enynes
8
16-enynes aromatic
8
c-h activation
8
esters c-h
4
activation highly
4
highly chemo-
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!