Traditional on-site wastewater treatment systems have proven to be unsuitable in areas of low permeability subsoils, representing a risk to human health and the environment. With large areas being covered by low permeability tills, Ireland needs to consider alternative treatment and disposal options to be able to allow further development in these areas and to deal with polluting legacy sites. The paper describes the development and structure of a geographic information system (GIS)-based decision support toolset to evaluate possible alternative strategies for these sites. The programme takes as its initial input the location of an existing house located in an area of low permeability subsoils. Through a series of interconnected GIS geoprocesses the model outputs appropriate solutions for a site, ranking them in terms of environmental sustainability and cost. However, the final decisions are still dependent on on-site constraints so that each solution is accompanied by an alert message that provides additional information for the user to refine the output list according to the available local site-specific information.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.2166/wst.2014.244 | DOI Listing |
Water Res
January 2025
Department of Chemical and Biomolecular Engineering, Yonsei University, 50, Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea. Electronic address:
Seawater reverse osmosis (SWRO)-pressure retarded osmosis (PRO) hybrid desalination system is being actively researched to reduce energy consumption by generating energy in the PRO. However, the SWRO-PRO hybrid system still faces the following challenges: low freshwater recovery and low energy generation. To resolve these challenges, this study first proposes a novel SWRO-Solar-driven desalination (SD)-PRO hybrid system for energy-efficient desalination.
View Article and Find Full Text PDFAdv Sci (Weinh)
January 2025
Dermatology Hospital, Southern Medical University, Guangzhou, 510091, China.
Sigal peptides have garnered remarkable efficacy in rejuvenating photoaged skin and delaying senescence. Nevertheless, their low solubility and poor permeability bring about a formidable challenge in their transdermal delivery. To address this challenge, bioactive ionic liquids (ILs) synthesized from natural glycyrrhizic acid (GA) and oxymatrine (OMT) with eminent biocompatibility is first prepared.
View Article and Find Full Text PDFBackground: Impaired Aβ clearance plays a key role in the common, late-onset AD. Anti-Aβ immunotherapies are controversial, in part because of high rates of serious side effects including edema, microhemorrhages, and siderosis, highlighting the importance of the development of alternative Aβ clearance strategy. Here, we introduce a bioinspired nanoparticle named MG-PE3 crossing the human blood-brain barrier (BBB) and clearing Aβ with no adverse effect.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Faculty of Health, Australian Research Centre in Complementary and Integrative Medicine, University of Technology Sydney, Ultimo, NSW, 2007, NSW, Australia.
Background: Alzheimer's Disease (AD) poses a substantial global health burden, necessitating innovative therapeutic strategies. This study investigates the neuroprotective potential of a chrysin-loaded Nanostructured Lipid Carrier (NLC) drug delivery system in AD management. Employing the high-pressure homogenization method, chrysin-loaded NLCs were meticulously formulated to optimize drug delivery efficiency.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Faculty of Health, Australian Research Centre in Complementary and Integrative Medicine, University of Technology Sydney, Ultimo, NSW, 2007, NSW, Australia.
Background: Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the impairment of cognitive development and disruption of neurocognitive function. This neuropathological condition is marked by neurodegeneration, loss of neural tissue, and the formation of neurofibrillary tangles and Aβ plaques. Various studies reported the utilization of phytoconstituents like fisetin, quercetin, berberine, and xanthohumol for the treatment of AD.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!