Background: Allergic rhinitis and asthma are chronic inflammatory conditions of airways sharing common pathophysiology. The two disorders have similar cellular responses, with different symptoms based on the differences in the physical structures involved. Studies have shown that allergic rhinitis has a major impact on asthma morbidity and that treating allergic rhinitis may also impact asthma control. The objective of this study was to determine association of allergic rhinitis with gender and asthma.
Methods: In this cross-sectional study, 100 patients with allergic rhinitis and equal number of patients without allergic rhinitis were included. Patients were excluded if they were smokers or if they had respiratory infection within the month preceding the study. Allergic rhinitis was diagnosed on history, nasal smear and blood complete picture. In both groups, patients having asthma, pre-diagnosed by the physician were isolated and their frequency was calculated.
Results: Ninety-two male and 108 female patients with mean age 30.72 +/- 12.58 were included in the study. Odds ratio for allergic rhinitis patients and asthmatics was 5.05 (p < 0.05). Association of allergic rhinitis with gender was also statistically significant (p < 0.05). Multiple regression analysis showed predictability of allergic rhinitis from asthma at p < 0.05.
Conclusion: Allergic rhinitis is significantly associated with gender and asthma.
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Niger Med J
January 2025
Health Sciences Research and Innovation Laboratory Medical School of Medicine & Pharmacy of Agadir, Ibn Zohr University, Agadir-Morocco.
Background: Asthma is a common chronic disease, and asthma control is the major therapeutic objective, thus ensuring a good health-related quality of life. This study aimed to evaluate the level of asthma control in a sample of asthmatic patients followed in allergology consultation during our training using the asthma control test (ACT) and its correlation with other parameters.
Methodology: This is a cross-sectional study of 66 asthmatic patients who were followed in pulmonology consultation at Agadir University Hospital after completing the asthma control test questionnaire over 6 months (June to December 2021).
Niger Med J
January 2025
Department of Otorhinolaryngology, Muhimbili University of Health and Allied Sciences, Dares Salaam, Tanzania.
Background: Pregnancy leads to physiological changes primarily driven by hormones like oestrogen and progesterone. Such changes are multi-systemic in nature including involvement of the ear, nose and throat. Such changes impair the quality of the life of pregnant women and thus requires prompt intervention during pregnancy.
View Article and Find Full Text PDFPostepy Dermatol Alergol
December 2024
Department of Public Health, Medical University of Warsaw, Warsaw, Poland.
Introduction: Due to their widespread character, allergic diseases are a significant challenge in the field of public health and clinical practice. The available clinimetric tools, including standardized and validated questionnaires, play an important role in determining the incidence of a particular allergic disease in the targeted population.
Aim: We attempted to evaluate the specificity and sensitivity of modified and standardized questions from the ISSAC and ECRHS questionnaires in the diagnosis of allergic diseases.
Allergy Asthma Clin Immunol
January 2025
Allergy Research Unit, Kingston Health Sciences Center - KGH Site, Kingston, ON, Canada.
Respir Res
January 2025
Department of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430022, China.
Background: Oxidative stress is key in inflammatory airway diseases. Heme oxygenase 1 (HMOX1) regulates oxidative stress, but its role in airway diseases needs exploration.
Methods: Differentially expressed genes (DEGs) between healthy nasal mucosa and chronic rhinosinusitis with nasal polyps (CRSwNP) were identified from Gene Expression Omnibus (GEO).
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