Fluoride is a naturally occurring mineral that can be obtained from foods and fluids originating from soils containing fluoride, as well as by drinking water that has been fluoridated. While consuming adequate fluoride intake can deliver benefits for dental and bone health, there have been concerns that excessive fluoride intake could lead to dental fluorosis, or even cause harm to bones. This article considers the balance of evidence in this area, and discusses the benefits and potential risks of fluoride in the UK diet. The role of tea as a major contributor to normal fluoride intake is highlighted, alongside some positive implications of this. Information is also provided to help nurses and midwives communicate the latest advice and guidance on fluoride to their patients.
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Broad-based targeted lipidomic analysis of dental fluorosis population in an adult population.
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College & Hospital of Stomatology, Anhui Medical University, Key Lab. of Oral Diseases Research of Anhui Province, No.81, Meishan Road, Shushan District, Hefei 230032, China. Electronic address:
Dental fluorosis, as a common chronic fluoride toxicity oral disease, is mainly caused by long-term excessive intake of fluoride, which seriously affects the aesthetics and function of patients' teeth. In recent years, with the rapid development of metabolomics technology, lipidomics, as an important means to study the changes in lipid metabolism in organisms, has shown great potential in revealing the mechanisms of disease development. As a major component of cell membranes and a signaling molecule, metabolic disorders of lipids are closely related to a variety of diseases, but the specific mechanism of action in dental fluorosis is still unclear.
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Department of Water Resource and Ecosystems, IHE Delft Institute for Water Education, Westvest 7, Delft, NH, Netherlands.
Groundwater is often used directly by the public in several river basins of India. Hence, this study was carried out with the objective of assessing the quality of groundwater in the Amaravathi basin, India, using a multiple indices approach. Groundwater quality data from 96 monitoring wells were obtained from the Central Groundwater Board and used in this study.
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Korea Institute of Geoscience and Mineral Resources, Daejeon, 34132, Republic of Korea.
Long-term intake of high-fluoride water can cause fluorosis in bones and teeth or damage to organs. Fluoride in groundwater is primarily derived from reactions with rocks containing fluorine-related minerals, and fluoride concentrations are elevated in groundwater that has been reacting with these rocks for a long time. The purpose of this study is to investigate the origin and distribution of fluoride in groundwater and to assess the influence of various factors, including geology, on fluoride concentrations in groundwater.
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Key Lab of Etiology and Epidemiology, Education Bureau of Heilongjiang Province & Ministry of Health (23618504), Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University, Harbin, Heilongjiang Province 150081, China. Electronic address:
Fluorine is a strong oxidizing element and excessive intake can have harmful effects, particularly on the body's calcified tissues. Recent studies have demonstrated a link between miRNA and fluorosis. This study aimed to evaluate the time-dose-effect relationship of miR-200c-3p in plasma, urine and cartilage of rats with drinking water fluorosis, and to explore its potential as a biomarker.
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Hebei Province Collaborative Innovation Center for Sustainable Utilization of Water Resources and Optimization of Industrial Structure, Hebei GEO University, Shijiazhuang, 050031, China.
Iodine and fluoride are essential trace elements for human health, with both deficiency and excess intake impacting well-being. This study investigates the groundwater funnel area in eastern Hengshui City, utilizing groundwater level and hydrochemical data from 2014 to 2022. Hydrogeochemical methods were employed to comprehensively analyze the evolution characteristics and causes of iodine and fluoride concentrations in the funnel area.
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