Our objective was to evaluate the effectiveness of adhesive glue in repairing first degree perineal tears. We conducted a noninferiority prospective, randomized, controlled trial comparing adhesive glue with traditional suturing. Each case was evaluated immediately after birth and after the puerperium. The two-sample t-test and the Mann-Whitney nonparametric test were applied to compare quantitative variables between the treatment groups. The chi-squared test and Fisher's exact test were used to assess the association between qualitative variables. A total of 102 women participated, 28 in the suture arm and 74 in the adhesive glue arm. While cosmetic and functional results of adhesive glue use were not inferior to suturing, the use of adhesive glue was associated with a shorter procedure, less need for local anesthetic, less pain, and greater satisfaction. Our results suggest a novel approach for the repair of common postpartum first degree lacerations. The use of adhesive glue achieves cosmetic and functional results equal to traditional suturing and offers some immediate advantages for the patient. While further clinical trials are needed to validate our results, it is important to inform obstetrician of the possible use of adhesive glue in these very common clinical scenarios. This trial is registered with NCT00746707.
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http://dx.doi.org/10.1155/2014/526590 | DOI Listing |
Ann Emerg Med
January 2025
Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada; Department of Pediatrics, Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, ON, Canada. Electronic address:
Study Objective: The peripheral intravenous catheter (IV) is the most common and painful invasive medical device in acute care settings. Our objective was to determine whether adding skin glue to secure IVs reduced catheter failure rate in children.
Methods: We conducted a randomized controlled trial in a tertiary-care pediatric emergency department (ED).
Angew Chem Int Ed Engl
January 2025
Sree Chitra Tirunal Institute for Medical Sciences and Technology, Bioceramics Division, Biomedical Technology Wing, 695011, Thiruvananthapuram, INDIA.
A collagen-inspired helical protein-mimic has been synthesized via topochemical polymerization of a designed tripeptide monomer. In the monomer crystal, molecules arrange in a head-to-tail manner, forming supramolecular helices. The azide and alkyne of adjacent molecules in the supramolecular helix are proximally preorganized in a ready-to-react arrangement.
View Article and Find Full Text PDFCureus
December 2024
Radiology, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS) Saveetha University, Chennai, IND.
Introduction Cosmetic surgery has advanced significantly, with wound closure techniques crucial for determining aesthetic and healing outcomes. Recently, cyanoacrylate glue and subcuticular sutures have gained attention for their unique benefits in cosmetic procedures. Cyanoacrylate glue, a non-invasive tissue adhesive, facilitates faster wound closure with minimal trauma, while subcuticular sutures offer durable, concealed closures, particularly suited for areas under mechanical stress.
View Article and Find Full Text PDFJ Cardiothorac Surg
January 2025
Cerrahpasa Medical Faculty, Department of Cardiovascular Surgery, Istanbul University-Cerrahpasa, Istanbul, Turkey.
Objectives: Despite the advances in medicine, aortic dissection remains a cardiac surgery emergency with high mortality and morbidity rates. This study examined the effects of the Glue + Felt technique, which uses biological glue and felt to repair the proximal anastomotic site, on the outcomes of patients with acute type A aortic dissection.
Methods: A total of 108 patients who underwent surgery for acute type A aortic dissection at our clinic between 2007 and 2020 were included in the study.
Langmuir
January 2025
School of Chemistry and Life Resources, Renmin University of China, 100872 Beijing, China.
Zwitterionic hydrogels exhibit excellent nonfouling and hemocompatibility. However, the practical application of these materials as antifouling coatings for biomedical devices is hindered by several key challenges, including the harsh preparation conditions and the weak coating stability. Here, we present a two-component zwitterionic hydrogel paint for the in situ preparation of robust zwitterionic hydrogel coatings on various substrate surfaces without UV assistance.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!