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Real-World Efficacy and Safety of Escalation to Weekly Adalimumab for Chronic Non-Infectious Uveitis: A Multicenter Study Involving Pediatric and Adult Patients.
Ocul Immunol Inflamm
January 2025
Department of Ophthalmology,University of Health Sciences, Ulucanlar Eye Training and Research Hospital, Ankara, Turkey.
Purpose: To evaluate the efficacy and safety of weekly adalimumab (ADA) treatment in non-infectious uveitis (NIU) patients, including both pediatric and adult populations, and identify factors influencing treatment efficacy.
Methods: A retrospective cohort study at two hospitals in Türkiye included 51 NIU patients (29 children, 22 adults) who escalated from bi-weekly to weekly ADA due to inadequate disease control. Data on six clinical parameters (anterior chamber reaction, vitreous haze, visual acuity, central macular thickness [CMT], prednisone use, uveitis flare-up frequency), adverse effects, and treatment-related factors were collected.
Central Corneal Subepithelial Haze Following Keratoplasty With Interrupted Sutures: A Novel Clinical Finding.
Int Med Case Rep J
January 2025
Anterior Segment Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
Purpose: This study aims to describe a newly identified clinical finding of central corneal subepithelial haze following keratoplasty (both penetrating and lamellar) with interrupted sutures, and to explore its causes and management strategies.
Methods: Case series.
Results: The study included 7 males and 3 females, with an average age of 24.
Green preparation of highly transparent nano-NH-UiO(Zr)-66/cellulose composite films with high-strength, superior flame retardant and UV to high-energy blue light shielding performance.
Int J Biol Macromol
January 2025
Engineering Research Center for Hemp and Product in Cold Region of Ministry of Education, School of Light Industry and Textile, Qiqihar University, Qiqihar 161006, PR China. Electronic address:
From the perspective of sustainable development and practical applications, there is a significant demand for the design of advanced cellulose-based film materials with superior mechanical, optical, and functional properties utilizing environmentally friendly strategies. Herein, biodegradable, mechanically robust and flame-retardant cellulose films with adjustable optical performance were successfully fabricated by in situ synthesis of NH-UiO(Zr)-66 via a DMF-free green process at room temperature. The results indicate that the introduction of NH-UiO(Zr)-66 enables films to realize a desirable flame retardancy (the limiting oxygen index (LOI) increased significantly from 19.
View Article and Find Full Text PDFMulticenter Analysis of Acute Retinal Necrosis: Clinical Characteristics, Viral Pathogens, and Diagnostic Predictive Factors.
Ocul Immunol Inflamm
January 2025
Ocular inflammation and infection division, Department of Ophthalmology, Phramongkutklao College of Medicine, Bangkok, Thailand.
Purpose: This multicenter study aimed to investigate the clinical characteristics and factors associated with specific viral pathogens in patients with acute retinal necrosis (ARN).
Methods: A retrospective multicenter cohort study included ARN patients who underwent aqueous or vitreous polymerase chain reaction (PCR) testing. Multivariable mixed-effects Poisson regression was used to identify factors associated with viral pathogens.
Hazy transparent cellulose nanocrystal-based films with tunable structural colors.
Carbohydr Polym
March 2025
State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, Jilin University, 2699 Qianjin Street, Changchun 130012, PR China. Electronic address:
Cellulose nanocrystals (CNCs) are powerful biosourced nanomaterials for the construction of chiral photonic films. While various techniques have been used to enrich the optical properties of such systems, surface roughness engineering has yet to be exploited to significantly modify their optical properties. In this work, by using vacuum filtration-assisted self-assembly, CNCs are densely packed into films with high optical transparency.
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