Plasmonic nanoparticles have been increasingly investigated for numerous applications in medicine, sensing, and catalysis. In particular, gold nanoparticles have been investigated for separations, sensing, drug/nucleic acid delivery, and bioimaging. In addition, silver nanoparticles demonstrate antibacterial activity, resulting in potential application in treatments against microbial infections, burns, diabetic skin ulcers, and medical devices. Here, we describe the facile, parallel synthesis of both gold and silver nanoparticles using a small set of poly(amino ethers), or PAEs, derived from linear polyamines, under ambient conditions and in absence of additional reagents. The kinetics of nanoparticle formation were dependent on PAE concentration and chemical composition. In addition, yields were significantly greater in case of PAEs when compared to 25 kDa poly(ethylene imine), which was used as a standard catonic polymer. Ultraviolet radiation enhanced the kinetics and the yield of both gold and silver nanoparticles, likely by means of a coreduction effect. PAE-templated gold nanoparticles demonstrated the ability to deliver plasmid DNA, resulting in transgene expression, in 22Rv1 human prostate cancer and MB49 murine bladder cancer cell lines. Taken together, our results indicate that chemically diverse poly(amino ethers) can be employed for rapidly templating the formation of metal nanoparticles under ambient conditions. The simplicity of synthesis and chemical diversity make PAE-templated nanoparticles useful tools for several applications in biotechnology, including nucleic acid delivery.
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http://dx.doi.org/10.1021/am5017073 | DOI Listing |
PeerJ
January 2025
Department of Biology, College of Science, Taif University, Taif, Saudi Arabia.
An innovative approach to ticks and insect pests management is necessary to mitigate the challenges posed by the indiscriminate use of chemical pesticides, which can lead to resistance development and environmental pollution. Despite their great potential, biological control agents have significant manufacturing, application, and stability limitations. Currently, using phytochemicals, biosynthesized nanoparticles, and bioagents to get rid of arthropods might be a good alternative that would make farmers less worried about residues and resistance.
View Article and Find Full Text PDFInt J Nanomedicine
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School of Pharmacy, Changzhou University, Changzhou, People's Republic of China.
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January 2025
CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai 200031, China. Electronic address:
Deoxynivalenol, a hazardous mycotoxin, poses significant health risks to humans and animals, necessitating highly sensitive detection methods due to its low abundance in food. Herein, we present a colorimetric sensing strategy for deoxynivalenol detection based on the inhibitory effect of silver ions on the peroxidase-like activity of Ni@Pt nanoparticles. Silver ions adsorb onto the surface of Ni@Pt nanoparticles, blocking the active site and consequently impeding their catalytic activity.
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
Departamento de Química Orgánica y Farmacéutica, Facultad de Farmacia, Universidad de Sevilla, Seville, Spain. Electronic address:
Titanium is widely used for implants however it presents limitations such as infection risk, stress shielding phenomenon, and poor osseointegration. To address these issues, a novel approach was proposed that involves fabricating porous titanium substrates, to reduce implant stiffness, minimizing stress shielding and bone resorption, and applying polymeric coatings to improve bioactivity. Composite coating prepared from chitosan, silver nanoparticles, and nanohydroxyapatite was optimized to enhance antibacterial properties and promote osseointegration.
View Article and Find Full Text PDFWaste Manag
January 2025
School of Chemistry and Chemical Engineering, Shanxi University, Taiyuan, 030006, China. Electronic address:
Coal fly ash, a waste byproduct of coal-fired power plants rich in silica, is produced in vast quantities, exceeding 750 million tons annually. This abundance underscores the importance of finding sustainable and value-added applications for its reuse. Silver nanoparticle-silica composites represent a class of inorganically hybrid antimicrobial agents as the protection layer of cotton fabrics.
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