Aim: To examine the oral mucosa under the denture base and to determine the influence of local factors that contribute to denture stomatitis.
Methods: In this prospective, case control study 30 patients with palatal inflammatory lesions were evaluated. A degree of palatal inflammation was scored. Swab samples were taken from tongue and palatal mucosa for microbiological examination. Denture plaque index, data of night wearing dentures, pH values of tongue and palatal mucosa were determined for all subjects.
Results: Significantly higher incidence of poor denture cleanliness index (p=0.01) and night wearing of dentures (p=0.009) were found in patients with denture stomatitis. There were significant differences between the groups in relation to the pH value of the tongue and palatal mucosa (p=0.016 and p=0.035, respectively). No significant association was found between denture stomatitis and microbiological findings, dentures age, type of dentures, presence of previous prosthesis, frequency or manner of dentures hygiene and smoking habits.
Conclusion: Poor denture hygiene, overnight wearing of dentures and oral mucosa pH less than 6.5 are predominant local etiologycal factors that contribute to denture stomatitis development.
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J Prosthet Dent
December 2024
Associate Professor, Department of Oral Medicine, Dental Research Center, Mazandaran University of Medical Sciences, Sari, Iran; Faculty of Dentistry, Mazandaran University of Medical Sciences, Sari, Iran. Electronic address:
Statement Of Problem: Denture stomatitis (DS) is a common oral disorder in patients with complete maxillary dentures. Typical treatments such as nystatin or azoles lead to drug resistance after a long period. Several studies have shown the antifungal activity of statins against Candida albicans; however, studies on the antifungal effect of atorvastatin against DS are lacking.
View Article and Find Full Text PDFInt Immunopharmacol
January 2025
Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Engineering Research Center of Oral Biomaterials and Devices of Zhejiang Province, 166th Qiutao Road, Hangzhou, 310000, China.. Electronic address:
Background: Oral manifestations function as precursors to potential systemic pathologies, signaling early indicators of underlying health complications or immunological dysfunctions. Within these dynamics, circulating inflammatory proteins are recognized as critical mediators in immunopharmacology, bridging holistic health, immune response, and oral health.
Methods: We employed genetic data from genome-wide association studies to perform comprehensive Mendelian randomization (MR) analyses on 91 circulating inflammatory proteins and 17 oral phenotypes.
J Oral Biol Craniofac Res
November 2024
Department of Oral Pathology, SRM Institute of Science and Technology, SRM dental college, Ramapuram campus, Chennai, TamilNadu, India, 600089.
Objectives: The objective of the study was to determine the antimicrobial efficacy of Lavandula angustifolia (True Lavender extract) towards Candida albicans, Streptococcus mutans, Staphylococcus aureus pathogens. Varying proportions of the extract was incorporated into polymethyl methacrylate (PMMA) denture base resin and the anti-adherent effect was investigated.
Methods: An in-vitro study was performed after pure extract was obtained from Lavandula angustifolia (LA) flowers using a solvent based hot extraction process.
Gerodontology
November 2024
Department of Oral Rehabilitation, University of Pernambuco (UPE) Faculty of Dentistry, Recife, Brazil.
J Prosthet Dent
October 2023
Clinical Professor, Division of Applied Oral Sciences and Community Dental Care, Faculty of Dentistry, The University of Hong Kong, Hong Kong, PR China.. Electronic address:
Statement Of Problem: Removable dental prosthesis cleanliness is multifactorial, and key clinical and nonclinical factors associated with prosthesis hygiene should be identified to inform practice, particularly given the dearth of studies relating specifically to prosthetic factors and prosthesis cleanliness.
Purpose: The purpose of this cross-sectional clinical study was to evaluate removable dental prosthesis cleanliness among community-dwelling elders by using a semi-automated planimetric assessment and to determine factors associated with removable prosthesis cleanliness.
Material And Methods: The cross-sectional study was conducted among community-dwelling elders wearing removable prostheses.
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