The OmpF porin gene expression in Yersinia pseudotuberculosis in response to antibiotics of two different classes (kanamycin and nalidixic acid) was analyzed using quantitative PCR and a fluorescence reporter system. Both antibiotics downregulated the expression of the ompF gene. The nalidixic acid significantly reduced ompF expression, while kanamycin, for which porins are considered to be an alternative transport route, only slightly reduced the ompF level.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
yersinia pseudotuberculosis
8
nalidixic acid
8
reduced ompf
8
[regulation yersinia
4
pseudotuberculosis major
4
major porin
4
expression
4
porin expression
4
expression response
4
response antibiotic
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!