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tailored confining microenvironment for lung cancer spheroids.
Mater Today Bio
April 2025
Shanghai Clinical Research and Trial Center, Shanghai Institute for Advanced Immunochemical Studies (SIAIS), ShanghaiTech University, Shanghai, 201210, China.
The mechanical properties and physical confinement of the extracellular matrix (ECM) are crucial roles in regulating tumor growth and progression. Extensive efforts have been dedicated to replicating the physical characteristics of tumor tissue by developing two-dimensional (2D) and three-dimensional (3D) models. However, it remains a significant challenge to modulate the local microenvironment around the specific cells according to the culture progress.
View Article and Find Full Text PDFEvolutionary implications of a deep-time perspective on insect pollination.
Biol Rev Camb Philos Soc
March 2025
Oxford University Museum of Natural History, Parks Road, Oxford, OX1 3PW, UK.
Plant pollination by insects represents one of the most transformative and iconic ecological relationships in the natural world. Despite tens of thousands of papers, as well as numerous books, on pollination biology published over the past 200 years, most studies focused on the fossil record of pollinating insects have only been published in the last few decades, and this field is still undergoing major developments. Current palaeontological evidence indicates that pollinating insects were diverse and participated in the reproduction of different gymnosperm lineages long before their association with flowering plants (angiosperms).
View Article and Find Full Text PDFNovel therapeutic strategies and recent advances in gut microbiota synergy with nanotechnology for colorectal cancer treatment.
Mater Today Bio
April 2025
Department of Radiotherapy, The Second Affiliated Hospital of Jilin University, Changchun, 130062, China.
Over the last two decades, molecular biology advances have revealed the gut microbiota's active and crucial role in colorectal cancer (CRC) pathogenesis and its dysregulation during tumorigenesis. This understanding has underscored the urgency of exploring novel therapeutic approaches to address the challenges posed by CRC. Among these approaches, nanosynergistic therapies, with their potential to modulate the gut microbiota, increase drug bioavailability and stability, and reduce side effects, have emerged as a promising avenue.
View Article and Find Full Text PDFRhodamine Based Chemosensors for Metal ions Detection: An Overview.
J Fluoresc
March 2025
Department of Chemistry, Guru Ghasidas Viswavidyalaya, Bilaspur, Chhattisgarh, 495009, India.
Today, water quality monitoring is crucial due to the health and environmental consequences of water pollution. Recently, various attempts have been made to construct rapid, sensitive, and selective heavy metal ion sensors. Fluorescent sensors are popular owing to their high specificity, sensitivity, and reversibility.
View Article and Find Full Text PDFKidney Transplant Evaluations-Why Put Off Until Tomorrow What You Can Do Today?
JAMA Intern Med
March 2025
Heersink School of Medicine, University of Alabama at Birmingham, Birmingham.
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