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Feasibility and impact of sentinel lymph node biopsy in patients affected by ano-rectal melanoma.
Tech Coloproctol
January 2025
Department of Surgical Sciences, University of Turin, Turin, Italy.
Introduction: Anorectal melanoma (ARM) is rare and highly lethal neoplasm. It has a poorer prognosis compared with cutaneous ones. Sentinel lymph node biopsy (SLNB) has become the preferred method of nodal staging method for cutaneous melanoma.
View Article and Find Full Text PDFBasic Science and Pathogenesis.
Alzheimers Dement
December 2024
UT Health San Antonio, San Antonio, TX, USA.
Background: Glycosylation is the most common post-translational modification in the brain. Aberrant glycosylation patterns are present in cerebrospinal fluid and brain tissue from Alzheimer's disease (AD) patients. Specifically, dysregulation of a particular form of terminal glycoconjugate modification, sialylation, has been identified in AD.
View Article and Find Full Text PDFGalvanic Cell-Stimulated Mesenchymal Stem Cell Mesh for Enhanced Pelvic Organ Prolapse Treatment.
Adv Healthc Mater
January 2025
Gansu Provincial Maternity and Child-Care Hospital, Lanzhou, 730050, China.
Implantation of a mesh loaded with mesenchymal stem cells (MSCs) is a common approach for the treatment of pelvic organ prolapse (POP). The mesh provides effective support to pelvic floor, enhancing muscle contraction of pelvic organs while reducing inflammation. In this study, a fully degradable mesh is designed for the treatment of POP, utilizing MSCs stimulated by a galvanic battery-powered electric field.
View Article and Find Full Text PDFMacrophage Migration Inhibitory Factor and Interleukin 1-β mRNA Levels as Predictors of Antidepressant Treatment Response in Major Depression.
Psychopharmacol Bull
January 2025
Oslin, MD, Veterans Integrated Service Network 4, Mental Illness Research, Education and Clinical Center, Crescenz Veterans Affairs Medical Center and Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.
Background: Immunologic measures have been studied as predictors of who will respond to standard antidepressants. Two previous, small studies of pretreatment leukocyte mRNA expression levels of the cytokines macrophage migration inhibitory factor (MIF) and interleukin 1-beta (IL1-β) identified antidepressant treatment responders.
Methods: We tested these findings in 1,299 patients from the PRIME Care study, a multi-center pharmacogenetic depression treatment trial.
Migration of a ureteral stent made from a nasogastric tube into the inferior vena cava: A case report.
Int J Surg Case Rep
December 2024
School of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
Introduction: This case report presents a rare instance of a ureteral stent, fashioned from a nasogastric tube, migrating into the inferior vena cava (IVC). The report underscores the importance of timely diagnosis and intervention to prevent severe complications.
Presentation Of Case: A 38-year-old woman presented with a ureteral stent, made from a nasogastric tube, found in the IVC following a previous surgery.
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