The first canine visceral leishmaniasis outbreak in Campinas, State of São Paulo Southeastern Brazil.

Rev Soc Bras Med Trop

Departamento de Medicina Preventiva e Social, Faculdade de Ciências Médicas, Universidade de Campinas, Campinas, SP, BRAZIL.

Published: October 2014

Introduction: Early detection of American visceral leishmaniasis (AVL) outbreak in animals is crucial for controlling this disease in non-endemic areas.

Methods: Epidemiological surveillance (2009-2012) was performed in Campinas, State of São Paulo, Brazil.

Results: In 2009, Leishmania chagasi was positively identified in four dogs. Entomological research and three serological studies (2010-2012) were undertaken as monitoring measures; these approaches revealed a moderate prevalence of Leishmania present in 4% of the canine population. Nyssomyia whitmani and Lutzomyia longipalpis were the predominant species identified.

Conclusions: Detection of an AVL outbreak in dogs in an area with an evolving natural landscape containing sand flies is crucial for control programs.

Download full-text PDF

Source
http://dx.doi.org/10.1590/0037-8682-0126-2013DOI Listing

Publication Analysis

Top Keywords

visceral leishmaniasis
8
campinas state
8
state são
8
são paulo
8
avl outbreak
8
canine visceral
4
leishmaniasis outbreak
4
outbreak campinas
4
paulo southeastern
4
southeastern brazil
4

Similar Publications

Leishmania is a genus of the family Trypanosomatidae that unites obligatory parasitic flagellates causing a variety of vector-borne diseases collectively called leishmaniasis. The symptoms range from relatively innocuous skin lesions to complete failures of visceral organs. The disease is exacerbated if a parasite harbors Leishmania RNA viruses (LRVs) of the family Pseudototiviridae.

View Article and Find Full Text PDF

In vitro and in silico approaches manifest the anti-leishmanial activity of wild edible mushroom .

In Silico Pharmacol

December 2024

Laboratory of Cell and Molecular Biology, Department of Botany, Centre of Advanced Study, University of Calcutta, 35 Ballygunge Circular Road, Kolkata, 700019 India.

Visceral Leishmaniasis, caused by is the second most deadly parasitic disease, causing over 65,000 deaths annually. Synthetic drugs available in the market, to combat this disease, have numerous side effects. In this backdrop, we aim to find safer antileishmanial alternatives with minimal side effects from mushrooms, which harbour various secondary metabolites with promising efficacy.

View Article and Find Full Text PDF

The analysis of the volatile compounds released by biological samples represents a promising approach for the non-invasive diagnosis of a disease. The present study, focused on a population of dogs infected with canine leishmaniasis, aimed to decipher the volatolomic profile associated with this disease in dogs, which represent the main animal reservoir for Leishmania pathogen transmission to humans. The volatiles emitted by the breath and hair of dogs were analysed employing the gas chromatography-mass spectrometry (GC-MS) technique.

View Article and Find Full Text PDF

Unlabelled: Visceral leishmaniasis (VL), caused by , remains challenging to treat due to severe side effects and increasing drug resistance associated with current chemotherapies. Our study investigates the anti-leishmanial potential of from Uttarakhand, India, with extracts prepared from leaves and stems using ethanol and hexane. Advanced GC-MS analysis identified over 100 bioactive compounds, which were screened using molecular docking to assess their binding to LdHEL-67, a DDX3-DEAD box RNA helicase of donovani.

View Article and Find Full Text PDF

Circular RNAs as a new perspective in the diagnosis and mechanism of Leishmania infections.

Acta Trop

December 2024

Department of Parasitology, Faculty of Medicine, Ege University, Izmir, Turkey; Department of Basic Oncology, Institute of Health Sciences, Ege University, Izmir, Turkey; Translational Pulmonary Research Center (EGESAM), Ege University, Izmir, Turkey. Electronic address:

Leishmaniasis is a neglected infectious disease that affects millions of people worldwide. Visceral leishmaniasis (VL) caused by Leishmania infantum and cutaneous leishmaniasis (CL) caused by L. major/ L.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!