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Nanopore back titration analysis of dipicolinic acid. | LitMetric

Nanopore back titration analysis of dipicolinic acid.

Electrophoresis

Department of Biological and Chemical Sciences, Illinois Institute of Technology, Chicago, IL, USA.

Published: February 2015

AI Article Synopsis

Article Abstract

Here, we report a novel label-free nanopore back titration method for the detection of dipicolinic acid, a marker molecule for bacterial spores. By competitive binding of the target analyte and a large ligand probe to metal ions, dipicolinic acid could be sensitively and selectively detected. This nanopore back titration approach should find useful applications in the detection of other species of medical, biological, or environmental importance if their direct detection is difficult to achieve.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511083PMC
http://dx.doi.org/10.1002/elps.201400255DOI Listing

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