End-stage kidney disease and kidney transplantation in HIV-positive patients: an observational cohort study.

J Acquir Immune Defic Syndr

*Department of Renal Sciences, King's College London, London, United Kingdom; †Research Department of Infection and Population Health, University College London, London, United Kingdom; ‡West London Centre for Sexual Health, Chelsea and Westminster Hospital NHS Foundation Trust, London, United Kingdom; §Imperial College Kidney and Transplant Centre, Imperial College Healthcare NHS Trust, London, United Kingdom; ‖UCL Centre for Nephrology, Royal Free Hospital NHS Foundation Trust, London, United Kingdom; ¶Department of Infectious Diseases, The Lothian University Hospitals NHS Trust, Edinburgh, United Kingdom; #Department of Sexual Health and HIV, Brighton and Sussex University Hospitals NHS Trust, Brighton, United Kingdom; and **Department of Sexual Health and HIV, King's College Hospital NHS Foundation Trust, London, United Kingdom.

Published: October 2014

End-stage kidney disease (ESKD) is a major complication of HIV infection. We observed a 3.8-fold increase in ESKD prevalence among black patients in the UK CHIC cohort during the 12-year study period. As of 2005, 107 patients had an ESKD diagnosis, 69 of whom (64%) were considered suitable for kidney transplantation (KT) and 34 (32%) had received a KT. Survival was similar for KT recipients and those awaiting KT (85% and 89% at 5 years, respectively; P = 0.53). Our results endorse the use of KT to manage ESKD in HIV-positive patients.

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Source
http://dx.doi.org/10.1097/QAI.0000000000000291DOI Listing

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