AI Article Synopsis
- Scientists are researching ways to use decellularized heart tissue to help heal hearts after a heart attack.
- They created a special method to remove cells from pig heart tissue while keeping its structure intact.
- They also built a machine that stimulates the heart tissue with movement and electrical signals to help it grow and develop properly.
Article Abstract
Cardiac tissue engineering/regeneration using decellularized myocardium has attracted great research attention due to its potential benefit for myocardial infarction (MI) treatment. Here we describe an optimal decellularization protocol to generate 3D porcine myocardial scaffolds with well-preserved cardiomyocyte lacunae and a multi-stimulation bioreactor that is able to provide coordinated mechanical and electrical stimulation for facilitating cardiac construct development.
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| http://dx.doi.org/10.1007/978-1-4939-1047-2_17 | DOI Listing |
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