Interests And Objectives: Patients' general practitioners (GPs) could be relevant consultants for collegial decisions of withholding or withdrawing treatment (WWT) defined by the Leonetti law. We therefore studied their implication by intensivists in end-of-life decisions and collected their feelings. Their wishes for the coming law revision were also investigated.
Methods: Retrospective descriptive study conducted in the polyvalent intensive care unit (ICU) of Longjumeau's hospital (France) using a distributed questionnaire to GPs of patients who benefited from collegial decisions of WWT in 2012.
Results: The response rate was 60.4% (32/53) and only 18.8% of the respondents participated as a consultant in WWT's decision for their patient. Two GPs out of three reported that they never participate in such decisions for their others patients. All uninvolved GPs did not contribute because intensivists did not consult them. Only 43.7% of GPs were contacted by intensivists during the stay and 21.9% at the discharge or death of their patient. GPs took news about their patient during ICU hospitalization in 37.5% of cases. Regarding uninvolved GPs, their participation could have changed WWT's decisions made for two patients (7.7%). Most respondents felt available (78.1%) and skilled (81.2 %) to participate in this kind of decision. A third was also questioned by the patient's family about it. Only 21.7% of GPs report to be familiar with the French end-of-life legislation. In case of a next revision, two thirds considered important to make the use of GPs obligatory in such decisions.
Conclusion: Despite an undeniable interest, GPs are rarely involved in collegial processes of WWT in ICUs, partially related to an insufficient knowledge of the law by the healthcare providers. At the dawn of end-of-life law's revision, their share could however improve our practices in this field.
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http://dx.doi.org/10.1016/j.lpm.2014.02.033 | DOI Listing |
Cell Host Microbe
January 2025
Department of Pathology, Microbiology, and Immunology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA. Electronic address:
Evidence suggests that bats are important hosts of filoviruses, yet the specific species involved remain largely unidentified. Niemann-Pick C1 (NPC1) is an essential entry receptor, with amino acid variations influencing viral susceptibility and species-specific tropism. Herein, we conducted combinatorial binding studies with seven filovirus glycoproteins (GPs) and NPC1 orthologs from 81 bat species.
View Article and Find Full Text PDFSci Total Environ
January 2025
Center for Water Research, Advanced Institute of Natural Sciences, Beijing Normal University, 519087 Zhuhai, China.
The new EU Urban Wastewater Treatment Directive requires stricter limits introducing quaternary treatments and poses significant challenges to achieving a sustainable environment. Advanced membrane-based treatment processes combined with mathematical models can be a good solution for facing the challenges above. Most existing literature on membrane filtration models primarily focuses on membrane bioreactors, lacking mechanistic models on ultrafiltration (UF) membranes.
View Article and Find Full Text PDFWorld J Gastrointest Oncol
January 2025
Department of Gastroenterology, Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai Institute of Digestive Diseases, Shanghai 200127, China.
Background: The relationship between autoimmune gastritis (AIG) and gastric polyps (GPs) is not well understood.
Aim: To explore the clinical characteristics and risk factors of AIG with GPs in patients.
Methods: This double center retrospective study included 530 patients diagnosed with AIG from July 2019 to July 2023.
BMC Prim Care
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Institute of General Practice and Family Medicine, University Hospital, LMU Munich, Munich, Germany.
Background: Approximately 20-25% of patients who survive medical treatment at an intensive care unit (ICU) develop post-traumatic stress symptoms. There is currently a gap in follow-up care for them. As part of the PICTURE study, general practitioners (GPs) carried out a brief interview-based intervention.
View Article and Find Full Text PDFCurr Biol
January 2025
Norwegian Institute for Nature Research (NINA), Trondheim 7034, Norway.
Understanding the movements of highly mobile animals is challenging because of the many factors they must consider in their decision-making. Many seabirds, for example, are adapted to use winds to travel long distances at low energetic cost but also potentially benefit from targeting specific foraging hotspots. To investigate how an animal makes foraging decisions, given the inevitable trade-off between these factors, we tracked over 600 foraging trips of breeding Manx shearwaters (Puffinus puffinus; N = 218 individuals) using GPS accelerometers.
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