Association between GUC2C and ADHD: evidence from both categorical and quantitative traits.

Psychiatry Res

Peking University Sixth Hospital/Institute of Mental Health, Beijing 100191, China; Key Laboratory of Mental Health, Ministry of Health, Peking University, Beijing 100191, China. Electronic address:

Published: December 2014

Guanylyl cyclase-C knock-out mice exhibit hyperactivity and attention deficits. We investigated seven single nucleotide polymorphisms (SNPs) of Guanylate cyclase 2C gene (GUC2C) in 381 ADHD trios and 382 healthy controls. Transmission disequilibrium tests (TDT), case-control studies and quantitative analyses indicated association between GUC2C with ADHD and its core symptoms.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.psychres.2014.06.051DOI Listing

Publication Analysis

Top Keywords

association guc2c
8
guc2c adhd
8
adhd evidence
4
evidence categorical
4
categorical quantitative
4
quantitative traits
4
traits guanylyl
4
guanylyl cyclase-c
4
cyclase-c knock-out
4
knock-out mice
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!