Intrinsic sphincter deficiency (ISD) is a pathologic condition that is diagnosed by using urodynamics to measure Valsalva leak point pressure and maximal urethral closure pressure. The diagnosis can be difficult to reach given natural discrepancies in these values in women of different age groups and with varying degrees of incontinence. By standardizing urodynamic methodologies and interpretations to better diagnosis women with ISD, it may be possible to improve preoperative planning and outcomes for these patients treated surgically with synthetic midurethral slings.
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