Daptomycin susceptibility of 833 strains of Gram-positive cocci from a university hospital in Japan (2009-2011).

Diagn Microbiol Infect Dis

Department of Microbiology and Infectious Diseases, Toho University School of Medicine, Tokyo 143-8540, Japan; Clinical laboratories Department, Toho University Medical Centre, Omori Hospital, Tokyo 143-8541, Japan.

Published: October 2014

The aim of this study was to confirm the daptomycin (DAP) susceptibility of bacteria isolated before the launch of DAP in Japan. DAP showed good activity against all 833 isolates (MIC90 = 0.25-0.5 mg/L for staphylococci, 0.5-4 mg/L for enterococci, and 0.25-0.5 mg/L for streptococci). This is the first report of the in vitro activity of DAP against Gram-positive cocci, including methicillin-resistant Staphylococcus aureus and enterococci, isolated in Japan.

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http://dx.doi.org/10.1016/j.diagmicrobio.2014.06.011DOI Listing

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