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Convenient synthesis of functionalized bis-ureidopyrimidinones based on thiol-yne reaction. | LitMetric
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Convenient synthesis of functionalized bis-ureidopyrimidinones based on thiol-yne reaction.

Hui-Qing Peng Cai-Li Sun Jiang-Fei Xu Li-Ya Niu Yu-Zhe Chen Li-Zhu Wu Chen-Ho Tung Qing-Zheng Yang

Chemistry

Key Laboratory of Photochemical Conversion and Optoelectronic Materials, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190 (P.R. China); University of the Chinese Academy of Sciences Beijing 100049 (P.R. China).

Published: September 2014

The preparation of functionalized bis-ureidopyrimidinones (Bis-UPy) through the thiol-yne reaction is described. Various Bis-UPys with different functional groups were synthesized by using the readily available functionalized alkynes and UPy-thiol to affirm the simplicity and versatility of the methodology.

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http://dx.doi.org/10.1002/chem.201402955DOI Listing

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