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The modified crABCDE treatment algorithm as recommendation in extreme cold.
Resusc Plus
January 2025
Department of Anesthesiology and Intensive Care Medicine, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Trauma care prioritizes life-threatening conditions using the ABCDE algorithm based on the principle "treat first what kills first". As for catastrophic hemorrhage, a leading preventable cause of death in trauma, modifications of this algorithm are necessary in specific cases. In cold climates, life-threatening hypothermia poses additional challenges.
View Article and Find Full Text PDFComplications After Transoral Surgery for Oropharyngeal Cancer: An ACS-NSQIP Database Study.
Laryngoscope
January 2025
Department of Otolaryngology-Head and Neck Surgery, Keck School of Medicine of USC, Los Angeles, California, U.S.A.
Objective: Prior studies have highlighted the risk of perioperative mortality due to catastrophic bleeding in patients receiving transoral surgery (TOS) for oropharyngeal squamous cell carcinoma (OPSCC). Although the 30-day mortality and morbidity remain low, understanding the risk factors associated with complications is still required. The goal of this study is to identify risk factors associated with complications after TOS for OPSCC using the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database.
View Article and Find Full Text PDFEvaluation of the effectiveness of road safety measures and their impact on the pattern and distribution of extracranial and intracranial hemorrhages in fatal head injury cases in Uttar Pradesh, India.
Natl J Maxillofac Surg
November 2024
Department of Forensic Medicine and Toxicology, King George's Medical University, Lucknow, Uttar Pradesh, India.
Introduction: In Uttar Pradesh, India, there are many fatal head injuries as a result of road traffic accidents (RTAs). Studying the pattern and distribution of intracranial hemorrhages, a frequent complication of severe head trauma might provide vital information on the efficacy of traffic safety regulations. To improve road safety tactics and lower fatal head injuries in Uttar Pradesh, this study intends to assess the effect of road safety measures on the frequency and distribution of intracranial hemorrhages in fatal head injury patients.
View Article and Find Full Text PDFFGF21 ameliorates diabetic nephropathy through CDK1-dependently regulating the cell cycle.
Front Pharmacol
January 2025
Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China.
Background: Diabetic nephropathy (DN) is a prevalent global renal illness and one of the main causes of end-stage renal disease (ESRD). FGF21 has been shown to ameliorate diabetic nephropathy, and in addition FGF-21-treated mice impeded mitogenicity, whereas it is unclear whether FGF21 can influence DN progression by regulating the cell cycle in diabetic nephropathy.
Methods: In order to create a diabetic model, STZ injections were given to C57BL/6J mice for this investigation.
Catastrophic iatrogenic abdominal aorta haemorrhage during anterior resection.
BMJ Case Rep
January 2025
General Surgery, Betsi Cadwaladr University Health Board, Bangor, UK
A woman in her 70s with hypertension, breast cancer and diverticulosis underwent laparoscopic anterior resection for a tubule-villous adenoma, converted to open Hartmann's with aorto-bi-iliac bypass due to a vascular injury. Intraoperative complications included haem-o-lok penetration of the calcified aorta, necessitating vascular team intervention. Postoperative issues included bilateral popliteal artery emboli requiring embolectomy and fasciotomy, and a parastomal abscess.
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