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Ileocecal Valve Metastasis Inducing Cecal Volvulus in a Patient With Lobular Breast Cancer: A Rare Cause of Bowel Obstruction.
Cureus
November 2024
General Surgery, Unidade Local de Saúde de Lisboa Ocidental, Lisbon, PRT.
Invasive lobular carcinoma (ILC) is the second most prevalent form of invasive breast cancer. Characterized by its insidious growth and distinctive histopathological features, ILC often presents with a less predictable metastatic pattern, including potential invasion of the gastrointestinal tract. This report presents the case of a patient with ILC who developed ileocecal valve metastasis leading to cecal volvulus, a rare but critical complication.
View Article and Find Full Text PDFA rare case of advanced gastric cancer with synchronous metastasis to the mucosal layer of the cecum and rectum.
Asian J Surg
November 2024
Department of General Surgery, The Third People's Hospital of Dalian, Dalian Medical University, Dalian, China. Electronic address:
Genetic profiling of metastatic colon adenocarcinoma in Iranian patients: Insights into pathogenic variants and tumor characteristics.
Cancer Genet
November 2024
Cancer Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Article Synopsis
- Colorectal cancer (CRC) is a major cause of cancer deaths, and this study examines the genetic profiles of 40 Persian patients with metastatic CRC to identify mutations in tumor-related genes.
- The research found that common mutations included variants in the APC and TP53 genes, with specific variants linked to different tumor locations, particularly KRAS with rectosigmoid and ERBB2 with colon cases.
- The results underline the genetic diversity in this population, emphasizing the need for personalized treatment strategies based on genetic findings.
Introduction And Importance: Low-grade appendicular mucinous neoplasms are rare. In contrast to other malignant tumors, they lack the ability for infiltrative growth or lymph node metastasis, but intraperitoneal mucin spread may lead to a life-threatening condition, known as a pseudomyxoma peritonei.
Case Presentation: Patient, a 47-year-old female, with complaints of a palpable mass in her right inguinal area, presented to our clinic.
Berberine inhibits colorectal liver metastasis via modulation of TGF-β in a cecum transplant mouse model.
Eur J Med Res
November 2024
East-West Cancer Center of Daejeon University, 176 Split 75 Daedeokdae-Ro Seo-Gu, Daejeon, 35235, Korea.
Background: Hepatic metastasis is the primary cause of colorectal cancer (CRC)-induced death. Our previous results showed the anti-metastatic effects of Coptidis rhizoma using in vitro model.
Aim: The present study aimed to investigate whether berberine, the main active compound of C.
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