[Systemic sclerosis: a multisystem disease].

Ned Tijdschr Geneeskd

Radboudumc, afd. Reumatische ziekten, Nijmegen.

Published: April 2015

AI Article Synopsis

  • Systemic sclerosis is a rare disease where the body’s immune system attacks its own tissues, causing issues in the skin and organs.
  • It can lead to serious problems like lung, kidney, heart, and blood pressure issues that can be very dangerous.
  • Getting early treatment with special medications can help stop the disease from getting worse and make people healthier.

Article Abstract

Systemic sclerosis is a rare, systemic autoimmune disease, characterized by inflammation, vasculopathy and fibrosis of the skin and internal organs. The disease is associated with a significantly increased morbidity and mortality, and can be rapidly progressive. Interstitial lung disease, renal hypertensive crisis, cardiac involvement and pulmonary arterial hypertension are life-threatening complications. Early treatment with immunosuppressive drugs can prevent progression and decrease morbidity and mortality.

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