Hippocampal place neurons not only represent current location, but fire in sequences that appear to simulate past and future spatial trajectories. A recent study has found that the firing sequences match the structure of a complex maze, suggesting that the structure of the environment is encoded by the place system, perhaps to aid navigational planning.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.cub.2014.06.001 | DOI Listing |
ACS Biomater Sci Eng
January 2025
J. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, Florida 32611, United States.
The complexation of nucleic acids and collagen forms a platform biomaterial greater than the sum of its parts. This union of biomacromolecules merges the extracellular matrix functionality of collagen with the designable bioactivity of nucleic acids, enabling advances in regenerative medicine, tissue engineering, gene delivery, and targeted therapy. This review traces the historical foundations and critical applications of DNA-collagen complexes and highlights their capabilities, demonstrating them as biocompatible, bioactive, and tunable platform materials.
View Article and Find Full Text PDFInt J Surg
January 2025
Department of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Background: Microsurgery demands an intensive period of skill acquisition due to its inherent complexity. The development and implementation of innovative training methods are essential for enhancing microsurgical outcomes. This study aimed to evaluate the impact of a simulation training program on the clinical results of fingertip replantation surgeries.
View Article and Find Full Text PDFDalton Trans
January 2025
School of Materials Science and Engineering, Jiangsu University of Science and Technology, Zhenjiang 212100, Jiangsu, China.
Five alkali metal manganese(III) fluorophosphates, KMn(POF)F (I), RbMn(POF)F (II), RbMn(POF)(PO)F (III), RbMn(POF)(PO)F (IV), and CsMn(POF)F (V), were successfully synthesized using a hydrothermal method. The monofluorophosphate anion (POF) groups work as "chemical scissors" to promote low-dimensional spin structures with the aid of alkali metal cations. I and II had an = 2 uniform chain structure formed by corner-sharing -MnOF octahedra.
View Article and Find Full Text PDF3D Print Med
January 2025
Department of Pediatric Cardiology, The Heart Institute, University of Colorado, Children's Hospital Colorado, 13123 E 16th Ave B100, 80045, Aurora, CO, USA.
Background: Despite advancements in imaging technologies, including CT scans and MRI, these modalities may still fail to capture intricate details of congenital heart defects accurately. Virtual 3D models have revolutionized the field of pediatric interventional cardiology by providing clinicians with tangible representations of complex anatomical structures. We examined the feasibility and accuracy of utilizing an automated, Artificial Intelligence (AI) driven, cloud-based platform for virtual 3D visualization of complex congenital heart disease obtained from 3D rotational angiography DICOM images.
View Article and Find Full Text PDFMol Biol Rep
January 2025
Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, No. 95, Yong An Road, Xi Cheng District, Beijing, 100050, China.
Canopy family proteins are highly sequence-conserved proteins with an N-terminal hydrophobic signal sequence, a unique pattern of six cysteine residues characteristic of the saposin-like proteins, and a C-terminal putative endoplasmic reticulum retention signal sequence. At present, the known canopy family proteins are canopy fibroblast growth factor signaling regulator 1 (CNPY1), CNPY2, CNPY3, and CNPY4. Despite similar structures, canopy family proteins regulate complex signal networks to participate in various biological processes.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!