Aim: To evaluate the feasibility of this novel surgical approach for treatment of cervical discitis and vertebral osteomyelitis.
Material And Methods: This is a report of two patients who underwent anterior cervical decompression for discitis and vertebral osteomyelitis (DVO) with cervical spine reconstruction with polymethylmethacrylate impregnated with antibiotics (AI-PMMA).
Results: Both patients had successful procedures that were followed by 6 weeks of intravenous antibiotics. Stabilization and eradication of infection was achieved with clinical and radiographic stabilization seen in both. Follow-up is greater than 18 months and both patients remain off antibiotics.
Conclusion: The described technique using AI-PMMA offers immediate structural stability and local delivery of high concentration of antibiotics. Use in two patients has demonstrated a cost effective, long-term biomechanically stable construct and infection control.
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http://dx.doi.org/10.5137/1019-5149.JTN.9380-13.0 | DOI Listing |
Spine (Phila Pa 1976)
December 2024
University of Missouri-Kansas City School of Medicine, 2411 Holmes St, Kansas City, MO 64108.
Study Design: Systematic Review and Network-Meta-analysis.
Purpose: This study aimed to systematically review the literature on management of primary osteomyelitis discitis and perform a network meta-analysis comparing the efficacy of different antibiotic treatment durations.
Background: Primary osteomyelitis discitis is a challenging condition with varying management strategies.
AJNR Am J Neuroradiol
December 2024
From the Department of Radiology (DGM., MVS., GMS., REG., JSR., TJR.) Mayo Clinic, Phoenix, AZ, USA; Department of Radiology (FED.), Mayo Clinic, Rochester, MN, USA. Department of Radiology (EHM.), Mayo Clinic, Jacksonville, FL, USA.
Background And Purpose: Studies show a modest yield for image-guided biopsy of suspected vertebral osteomyelitis-discitis. Many studies evaluate factors to improve diagnostic yield, and few studies assess how biopsy results impact clinical management. We aim to evaluate the impact of biopsy results on clinical management in suspected vertebral osteomyelitis-discitis.
View Article and Find Full Text PDFBMC Infect Dis
December 2024
108 Military Central Hospital, Vietnamese - German Center for Medical Research (VG-CARE), N 1, Tran Hung Dao Str., Hai Ba Trung Dist, Hanoi, 1000, Vietnam.
Citrobacter youngae (C. youngae) was first described in 1993, and data suggesting that human diseases caused by this bacterium remain scarce. Reports on C.
View Article and Find Full Text PDFJ Neurosurg Spine
December 2024
1Department of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences at University at Buffalo, New York.
Objective: The escalating incidence of de novo spinal infections poses a substantial neurological impact on patients. This has prompted a growing interest in discerning which patients would derive greater benefit from medical as opposed to surgical management of these occurrences. The authors assessed the predictive applicability of the Spinal Infection Treatment Evaluation (SITE) score in discerning between surgical intervention and medical management.
View Article and Find Full Text PDFCureus
November 2024
Internal Medicine, University of Michigan, Ann Arbor, USA.
Coronavirus disease 2019 (COVID-19) has been associated with numerous complications beyond the respiratory tract, including spinal and joint co-infections and secondary infections. However, we could not locate any reported cases of bilateral shoulder infections with additional spinal infections associated with mild (like our patient) COVID-19 or with more severe cases of COVID-19. We report the case of a healthy 62-year-old male who presented with mild COVID-19 and concurrent methicillin-sensitive (MSSA) bacteremia associated with multiple musculoskeletal sites of deep-seated infection.
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