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Effects of Bifidobacterium bifidum G9-1 on Nasal Symptoms in a Guinea Pig Model of Experimental Allergic Rhinitis. | LitMetric

Effects of Bifidobacterium bifidum G9-1 on Nasal Symptoms in a Guinea Pig Model of Experimental Allergic Rhinitis.

Biosci Microflora

Biofermin Kobe Research Institute, Biofermin Pharmaceutical Co., Ltd., 7-3-4 Higashi-machi, Ibukidai, Nishi-ku, Kobe 651-2242, Japan.

Published: July 2014

AI Article Synopsis

  • Recent studies have shown that probiotics can help reduce allergic responses in animals, but limited research has focused on their effects on nasal allergy symptoms specifically.
  • This study tested the probiotic Bifidobacterium bifidum G9-1 (BBG9-1) on guinea pigs with allergic rhinitis to assess its impact on symptoms like sneezing and nasal blockage.
  • Results indicated that oral intake of BBG9-1 significantly reduced these nasal allergy symptoms, suggesting it could be a beneficial treatment for people with allergic rhinitis.

Article Abstract

Recent studies of several animal models have shown beneficial effects of probiotics against allergic responses. However, few reports have examined the effects of probiotics on allergic nasal symptoms such as sneezing and nasal obstruction in animal models of allergic rhinitis. This study evaluated the efficacy of Bifidobacterium bifidum G9-1 (BBG9-1) on antigen-induced nasal symptoms using guinea pig models of allergic rhinitis. Oral administration of BBG9-1 significantly inhibited antigen-induced allergic nasal reactions such as sneezing and nasal obstruction. Our results suggest that BBG9-1 may be useful for alleviating nasal symptoms in patients with allergic rhinitis.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103633PMC
http://dx.doi.org/10.12938/bifidus.30.1DOI Listing

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