Purpose: To determine the distribution of ocular biometric components and their correlation with age and sex during the ages of ocular development in a 6- to 18-year-old population in Iran.
Method: In this cross-sectional study, which was performed in October 2012, multi-stage stratified cluster sampling was used to sample the study population from Dezful schools, a city in the southwest of Iran. Biometric examinations were done by an experienced optometrist using the LENSTAR/BioGraph (WaveLight AG, Erlangen, Germany).
Results: Among 864 selected students, 683 participated in the study (response rate: 79.1%); 377 participants (55.2%) were male, and the mean age of the participants was 12 ± 3.4 years (range: 6-18 years). The mean and 95% confidence interval of axial length (AL) were 23.13 mm (22.93-23.33), anterior chamber depth (ACD) was 3.01 mm (2.96-3.06), lens thickness (LT) was 3.58 mm (3.55-3.61), central corneal thickness (CCT) was 549.33 mic (546.59-552.07), corneal radius (CR) was 7.77 mm (7.74-7.81), corneal diameter (CD) was 12.34 mm (12.31-12.38) and pupil diameter (PD) was 4.97 (4.91-5.03). Mean AL, ACD, CD and CR were significantly higher in boys, and mean LT was significantly higher in girls. AL and ACD increased, while LT decreased significantly with age. Myopia was associated with an increase in AL and ACD, and hyperopia was associated with an increase in LT and a decrease in ACD.
Conclusion: This study evaluated the distribution of the biometric components of the eye during the ages of ocular development in an Iranian population. In this age range, the majority of the changes were observed in the AL and LT.
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http://dx.doi.org/10.1111/aos.12498 | DOI Listing |
Invest Ophthalmol Vis Sci
January 2025
Institute for Applied Mathematics, University of Bonn, Bonn, Germany.
Purpose: To quantify outer retina structural changes and define novel biomarkers of inherited retinal degeneration associated with biallelic mutations in RPE65 (RPE65-IRD) in patients before and after subretinal gene augmentation therapy with voretigene neparvovec (Luxturna).
Methods: Application of advanced deep learning for automated retinal layer segmentation, specifically tailored for RPE65-IRD. Quantification of five novel biomarkers for the ellipsoid zone (EZ): thickness, granularity, reflectivity, and intensity.
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Background: The ciliary muscle is known to play a part in presbyopia, but the mechanism has not received a comprehensive review, which this study aims to achieve. We examined relevant articles published from 1975 through 2022 that explored various properties of the muscle and related tissues in humans and rhesus monkeys. These properties include geometry, elasticity, rigidity, and composition, and were studied using a range of imaging technologies, computer models, and surgical methods.
View Article and Find Full Text PDFOphthalmic Plast Reconstr Surg
October 2024
Division of Ophthalmology, Children's Hospital of Philadelphia.
Background: Punctal agenesis (PA) is a rare congenital anomaly that can occur in isolation or as part of an underlying syndrome. The benefit of genetic assessment in individuals with PA and clinical features that should prompt molecular workup has not been systematically studied. The aim of this study was to identify ocular and extraocular features associated with PA and determine its association with an underlying syndrome.
View Article and Find Full Text PDFJ Family Med Prim Care
November 2024
Department of Public Health, College of Medicine, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia.
Background: Ocular allergy (OA) is one of the most common disorders worldwide, affecting millions of individuals of all ages. Public education about the disease is critical for lowering the prevalence of OAs. The present study aims to evaluate the knowledge and awareness level of OA among undergraduate students at Imam Mohammed Ibn Saud Islamic University in Riyadh, Saudi Arabia.
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