AI Article Synopsis
- Vicinal diamines are crucial in organic chemistry due to their presence in many biological and pharmaceutical compounds.
- An efficient, metal-free method for intramolecular diamination is introduced, utilizing a new chiral hypervalent iodine reagent.
- This reagent proves to be an effective catalyst for synthesizing various diamines with high stereoselectivity.
Article Abstract
Vicinal diamines constitute one the most important functional motif in organic chemistry because of its wide occurrence in a variety of biological and pharmaceutical molecules. We report an efficient metal-free, highly stereoselective intramolecular diamination using a novel chiral hypervalent iodine reagent together with its application as an efficient catalyst for the synthesis of diamines.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736455 | PMC |
| http://dx.doi.org/10.1002/chem.201403891 | DOI Listing |
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