We present a case of near-normalization of the QRS by septal pacing in a patient with dual-chamber pacemaker and underlying complete right bundle branch block and first degree atrioventricular block. The right ventricular mechanical synchronization suggested by the ECG was validated as such by strain echo. To the best of our knowledge, this is the first time it has been shown that the narrowing of the QRS corresponds to mechanical synchronization in a case of this seldom-recognized phenomenon.
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http://dx.doi.org/10.1111/anec.12184 | DOI Listing |
J Chem Phys
March 2025
Department of Physics, University of Houston, Houston, Texas 77204, USA.
We consider the quantum dynamics of a pair of coupled quantum oscillators coupled to a common correlated dissipative environment. The resulting equations of motion for both the operator moments and covariances can be integrated analytically using the Lyapunov equations. We find that for fully correlated and fully anti-correlated environments, the oscillators relax into a phase-synchronized state that persists for long-times when the two oscillators are nearly resonant and (essentially) forever if the two oscillators are in resonance.
View Article and Find Full Text PDFBiophys Rev
February 2025
Yale Cardiovascular Research Center, Section of Cardiovascular Medicine Department, New Haven, CT USA.
The maturation of human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) is pivotal for their potent application in regenerative medicine, drug screening, and disease modeling. While the emergence of hiPSC-CMs solved the inadequacy of cardiomyocytes in cardiovascular research, they frequently remain immature: more closely resembling fetal rather than adult cardiomyocytes. This immaturity limits their functional utility in both laboratorial and clinical practices.
View Article and Find Full Text PDFSci Rep
March 2025
Department of Mechanical Engineering, Qinghai University, Xining, 810016, China.
In response to the difficulty in predicting the change of bolt preload when using torque method to load bolt, this paper proposes a bolt preload prediction method based on mechanism and data fusion calculation for hexagonal end face bolt, and establishes a tightening prediction model based on machine learning method. Firstly, a tightening mechanism model is established, revealing the reasons why bolt preload is difficult to predict and errors cannot be eliminated. Secondly, sensitivity evaluation indicator is established to conduct parameter sensitivity analysis, and the fusion method of "mechanism model guiding data model to perform feature selection" is determined.
View Article and Find Full Text PDFChemistry
March 2025
Indian Institute of Science Education and Research Thiruvananthapuram, School of Chemistry, Maruthamala PO Vithura, 695551, Thiruvananthapuram, INDIA.
Controlling synchronized motion and transmission of molecular motion to a remotely located guest is not trivial. Here, we demonstrate a light-triggered, scissor-like conformational change in a molecular plier to reversibly alter the conformation and helical chirality of a noncovalently bound rotor guest. The plier comprises three building blocks: an azobenzene unit that controls the open-close motion of the plier upon light-activated isomerization from E to Z, a BINOL unit that serves as both a hinge and a chiral inducer and two pyridine moieties that can form a complex with the rotor guest.
View Article and Find Full Text PDFJ Environ Sci (China)
August 2025
College of Resources and Environment, University of Chinese Academy of Sciences, Beijing 101408, China; Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China. Electronic address:
A sensor, serving as a transducer, produces a quantifiable output in response to a predetermined input stimulus, which may be of a chemical or physical nature. The field of gas detection has experienced a substantial surge in research activity, attributable to the diverse functionalities and enhanced accessibility of advanced active materials. In this work, recent advances in gas sensors, specifically those utilizing Field Effect Transistors (FETs), are summarized, including device configurations, response characteristics, sensor materials, and application domains.
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