Bipotent or Oligopotent? A macrophage and DC progenitor revisited.

Immunity

Department of Biodefense Research, Medical Research Institute, Tokyo Medical and Dental University, Tokyo 113-8510, Japan. Electronic address:

Published: July 2014

Macrophage and dendritic cell (DC) progenitors (MDPs) produce macrophages and DCs but not other hematopoietic lineages. In this issue of Immunity, Sathe et al. (2014) show that isolated MDP populations hardly contain such bipotent progenitors at clonal levels, arguing against the existence of MDPs.

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http://dx.doi.org/10.1016/j.immuni.2014.07.004DOI Listing

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