Regulatory T cells: exosomes deliver tolerance.

Immunity

Section of Rheumatology, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI 53226, USA.

Published: July 2014

T regulatory (Treg) cells enforce peripheral tolerance through regulation of diverse immune responses in a context-specific manner. Okoye et al. show one way that Treg cells suppress Th1 cell responses is through nonautonomous gene silencing mediated by microRNA-containing exosomes.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130330PMC
http://dx.doi.org/10.1016/j.immuni.2014.07.001DOI Listing

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