T regulatory (Treg) cells enforce peripheral tolerance through regulation of diverse immune responses in a context-specific manner. Okoye et al. show one way that Treg cells suppress Th1 cell responses is through nonautonomous gene silencing mediated by microRNA-containing exosomes.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130330 | PMC |
http://dx.doi.org/10.1016/j.immuni.2014.07.001 | DOI Listing |
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