Radiation dose reduction in CT-guided spine biopsies does not reduce diagnostic yield.

AJNR Am J Neuroradiol

From the Department of Radiology, Icahn School of Medicine, Mount Sinai Health System, New York, New York.

Published: December 2014

Background And Purpose: CT-guided biopsy is the most commonly used method to obtain tissue for diagnosis in suspected cases of malignancy involving the spine. The purpose of this study was to demonstrate that a low-dose CT-guided spine biopsy protocol is as effective in tissue sampling as a regular-dose protocol, without adversely affecting procedural time or complication rates.

Materials And Methods: We retrospectively reviewed all patients who underwent CT-guided spine procedures at our institution between May 2010 and October 2013. Biopsy duration, total number of scans, total volume CT dose index, total dose-length product, and diagnostic tissue yield of low-dose and regular-dose groups were compared.

Results: Sixty-four patients were included, of whom 31 underwent low-dose and 33 regular-dose spine biopsies. There was a statistically significant difference in total volume CT dose index and total dose-length product between the low-dose and regular-dose groups (P < .0001). There was no significant difference in the total number of scans obtained (P = .3385), duration of procedure (P = .149), or diagnostic tissue yield (P = .6017).

Conclusions: Use of a low-dose CT-guided spine biopsy protocol is a practical alternative to regular-dose approaches, maintaining overall quality and efficiency at reduced ionizing radiation dose.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7965327PMC
http://dx.doi.org/10.3174/ajnr.A4053DOI Listing

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