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A "tailored" interventional and surgical management for moderate to critical acute pancreatitis in late phase: a cohort study.

Langenbecks Arch Surg

November 2022

General Surgery Unit, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Via Paradisa 2, 56124, Pisa, Italy.

Purpose: Several interventional procedures are available to treat moderate-to-critical acute pancreatitis (AP) in its late phase. The ongoing debate on these options, together with the scarcity of reported quality of life (QoL) information in the Literature, prompted us to conduct a review of our experience.

Methods: All the patients treated at our referral Center for moderate-to-critical AP according to Determinant-Based Classification (DBC) were retrospectively reviewed.

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Data mining and metagenomic analysis of 277 open reading frame sequences of bipartite RNA viruses of the genus Nepovirus, family Secoviridae, were performed, documenting how challenging it can be to unequivocally assign a virus to a particular species, especially those in subgroups A and C, based on some of the currently adopted taxonomic demarcation criteria. This work suggests a possible need for their amendment to accommodate pangenome information. In addition, we revealed a host-dependent structure of arabis mosaic virus (ArMV) populations at a cladistic level and confirmed a phylogeographic structure of grapevine fanleaf virus (GFLV) populations.

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Objectives: To validate the Modified Determinant-Based Classification (MDBC) system, and compare it with the Revised Atlanta Classification (RAC) and the Determinant-Based Classification (DBC).

Methods: Prospective observational research was conducted in 35 international intensive care units, on patients with acute pancreatitis, and at least 1 organ failure (OF). Patient classification according to the MDBC was as follows: group 1 (transient OF, without local complications [LCs]), group 2 (transient OF and LC), group 3 (persistent OF, without LC), and group 4 (persistent OF and LC).

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Background: Early risk stratification of acute pancreatitis is crucial to improve clinical outcomes. The objective of this study was to evaluate the ability of pancreatic stone protein (PSP) to predict acute pancreatitis severity and to compare it with the biomarkers and severity scores currently used for that purpose.

Patients And Methods: Prospective single-center observational study enrolling 268 adult patients with acute pancreatitis.

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[A nationwide survey of acute pancreatitis:a report from 126 hospitals in China].

Zhonghua Wai Ke Za Zhi

August 2021

Department of General Surgery,Xuanwu Hospital,Capital Medical University; Clinical and Research Center for Acute Pancreatitis, Capital Medical University; National Clinical Research Center for Geriatric Diseases,Ministry of Science and Technology,Beijing 100053,China.

To investigate the current status of acute pancreatitis(AP) diagnosis and treatment in hospitals of different levels in China. A cross-sectional survey was conducted. The was designed and sent to the members of the Group of Pancreatic Surgery Chinese Society of Chinese Medical Association Branch and some other hospitals online from 8 to 24 December, 2020.

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