AI Article Synopsis
- EGCG, a key component of green tea, inhibits tumor promotion in mouse skin during carcinogenesis.
- EGCG also shows effectiveness in preventing tumor development in the gastrointestinal tract using a specific mouse model for duodenal cancer.
- The study utilized both stereomicroscopic and histological methods to analyze the duodenal tumors that formed.
Article Abstract
(-)-Epigallocatechin gallate (EGCG) is the main polyphenolic constituent of green tea infusion and inhibits tumor promotion by teleocidin in two-stage carcinogenesis on mouse skin. In this work, EGCG was found to inhibit tumor promotion in the gastrointestinal tract in a model system of mouse duodenal carcinogenesis with N-ethyl-N'-nitro-N-nitrosoguanidine. The duodenal tumors that developed were studied stereomicroscopically and histologically.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917795 | PMC |
| http://dx.doi.org/10.1111/j.1349-7006.1989.tb01666.x | DOI Listing |
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