Targeted therapies have produced significant treatment advances for patients diagnosed with a variety of tumor types. These therapies are associated with unique dermatologic toxicities that may hamper treatment efforts and cause significant discomfort for patients. Prevention and management of these toxicities can allow patients to remain on therapy and hence receive maximum clinical benefit from the drug.
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http://dx.doi.org/10.6004/jadpro.2012.3.3.2 | DOI Listing |
Biomol Concepts
January 2025
Division of Pharmacology, School of Medical and Life Sciences, Sunway University, No. 5, Jalan Universiti, Bandar Sunway, 47500 Selangor Darul Ehsan, Malaysia.
Seaweeds have been utilized as food, fodder, fertilizer, and medicine since ancient times; nevertheless, they have received only a little attention. In the current work, we extracted the sulfated polysaccharide from a marine source and investigated its anti-arthritic potential . The isolated and freeze-dried polysaccharide was tested for acute oral toxicity based on OECD 423.
View Article and Find Full Text PDFSci Rep
January 2025
Key Laboratory of Marine Ecosystem Dynamics, Second Institute of Oceanography, Ministry of Natural Resources, 36 Baochubei Road, Hangzhou, 310012, People's Republic of China.
The increasing economic damage caused by terrestrial gastropods, especially the Monacha cartusiana (M. cartusiana) land snail, to the agricultural sector requires a diligent and continuous search for new materials and alternatives for the control operations. In this piece of work, a magnetically separable molluscicide with high effectiveness green Barium-Cerium-Copper ferrite/TiO (Ba-Ce-CuFO/TiO) nanocomposite was greenly prepared using Eichhornia plant aqueous extract and characterized using different techniques.
View Article and Find Full Text PDFClin Cosmet Investig Dermatol
January 2025
Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran-Dr Hasan Sadikin Hospital, Bandung, West Java, Indonesia.
Epidermal growth factor receptor inhibitors (EGFRI) are biological factors used in several types of cancer, including non-small-cell lung cancers (NSCLC). One of the EGFR inhibitors that has been approved for NSCLC is afatinib. Dermatologic adverse events are the most commonly reported and may impair the patient's compliance to the therapy as it causes aesthetic discomfort and significantly impact the patient's quality of life.
View Article and Find Full Text PDFBull Environ Contam Toxicol
January 2025
Division of Environmental Science and Ecological Engineering, Korea University, Seoul, 02841, Republic of Korea.
The adverse effect of chemical additives leaching from microplastics (MPs) on Daphnia magna populations is not fully understood. In this study, D. magna populations were exposed to polyethylene (PE) MP fragments (5.
View Article and Find Full Text PDFBMJ Case Rep
January 2025
Emergency Medicine Department, King Abdulaziz Medical City in Riyadh, Riyadh, Saudi Arabia.
A woman in her 40s with a history of depression, diabetes, zinc deficiency and gastric bypass surgery presented to the emergency department following the intentional ingestion of ninety 50 mg tablets of zinc sulfate. She exhibited gastrointestinal distress without systemic toxicity. Imaging revealed radiopaque tablets in the abdomen, and her management was primarily supportive, focusing on symptom control and hydration.
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