Decidua and implantation of the embryo from a historical perspective.

Int J Dev Biol

Department of Pathology and Laboratory Medicine, The University of Kansas School of Medicine, Kansas City, Kansas, USA.

Published: March 2015

AI Article Synopsis

  • - Implantation of embryos is essential for early development and relies on a specially prepared uterus known as the decidualized uterus.
  • - The article reviews modern ideas about decidualization and embryonic implantation, highlighting their interconnectedness.
  • - Arthur T. Hertig and John Rock's 15 years of research in Boston laid the groundwork for understanding human implantation, reproductive biology, infertility, and contraception.

Article Abstract

Implantation of the embryo is critical for the initiation of intrauterine development of early embryos. It depends on the proper soil formed by the decidualized pregnant uterus. In the present article I have reviewed the evolution of the modern concepts of decidualization and embryonic implantation, emphasizing how closely interrelated these two processes are. Special emphasis and recognition is given to the Boston pathologist Arthur T. Hertig, who studied for 15 years with another Bostonian, John Rock, a gynecologist, human implantation and early embryogenesis, thus providing the basis for future studies of human reproductive biology, infertility and contraception.

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Source
http://dx.doi.org/10.1387/ijdb.140075idDOI Listing

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