AI Article Synopsis

  • The study investigates the expression of MKK6 protein in solid tumors, which has not been previously explored.
  • Using western blotting and immunofluorescence, researchers found elevated levels of MKK6 in Esophageal, Stomach, and Colon cancers compared to control samples.
  • The findings suggest that MKK6 could serve as a potential diagnostic or prognostic marker for these types of cancer.

Article Abstract

Expression analysis of MKK6 protein in solid tumors has never been investigated. Here, we report systematic analysis of MKK6 protein in different types of human tumor samples using western blotting and immunofluorescence techniques. We observed significant increase in the expression of MKK6 in Esophageal, Stomach, and Colon cancers as compared to controls. Results were alternately confirmed by Immunofluorescence studies. Upregulation of MKK6 protein is indicative of its role in human cancers and could possibly be used as a novel diagnostic or prognostic marker in these cancers.

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http://dx.doi.org/10.3109/07357907.2014.933236DOI Listing

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