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Delayed Stevens-Johnson syndrome induced by combined administration of carbamazepine and botulinum toxin: A case report.
Medicine (Baltimore)
January 2025
Department of Rehabilitation Medicine, Hebei General Hospital, Shijiazhuang, Hebei, China.
Rationale: Steven-Johnson syndrome (SJS) is characterized by severe illness, rapid progression, and high mortality rates, with the vast majority of cases induced by medications. Botulinum toxin, a neurotoxin produced by Clostridium botulinum, has not been reported in the literature as a causative agent of SJS.
Patient Concerns: A 56-year-old male patient, who underwent surgery for cerebral hemorrhage, developed widespread patchy annular papules following the injection of botulinum toxin into the masseter muscle.
[IgA vasculitis with necrosis of the small intestine secondary to monoclonal gammopathy of renal significance: A case report].
Beijing Da Xue Xue Bao Yi Xue Ban
December 2024
Department of Rheumatology and Immunology, Peking University Shougang Hospital, Beijing 100144, China.
Monoclonal gammopathy of undetermined significance combined with renal damage is named monoclonal gammopathy of renal significance. There are few reports about IgA vasculitis in patients with monoclonal gammopathy of undetermined significance. Here, we report a case of monoclonal gammopathy of renal significance, who had manifestations of IgA vasculitis, including purpura, gastrointestinal bleeding and joint pain.
View Article and Find Full Text PDFCytomegalovirus Enterocolitis in a Patient Treated with Methylprednisolone for Amiodarone Hypersensitivity Pneumonitis.
Diagnostics (Basel)
November 2024
Department of Endocrinology and Diabetology, University Medical Centre Maribor, Ljubljanska Ulica 5, 2000 Maribor, Slovenia.
Cytomegalovirus (CMV) is a common cause of infection in immunocompromised individuals, such as patients with hematological malignancies or AIDS, but can also occur in patients with other acquired immunodeficiencies. In tissue-invasive diseases, CMV diagnosis requires CMV DNA in the plasma and the histological confirmation of CMV in a tissue or organ. Evidence of CMV colitis requires a characteristic endoscopic picture with ulcers with a well-defined, convex appearance and CMV viral inclusions in the form of an "owl's eye" on mucosal sections stained with hematoxylin and eosin.
View Article and Find Full Text PDFDupilumab combined with corticosteroid therapy for Kimura disease with multiple systemic masses: a case report and literature review.
Front Immunol
November 2024
Department of Dermatology, Shenzhen University General Hospital, Shenzhen, Shenzhen, China.
Article Synopsis
- Kimura's disease (KD) is a rare condition with unclear causes, no standardized diagnostic criteria, and varied clinical presentations, leading to ongoing research for optimal treatment strategies.
- The paper discusses a case of a 37-year-old Chinese woman who experienced 12 years of skin issues and limb swelling before being diagnosed with KD, resulting in a specific treatment plan combining dupilumab and oral corticosteroids.
- After treatment, the patient had significant improvements with reduced nodules and lower levels of serum IgE, eosinophils, and basophils, indicating the effectiveness of the combined therapy for KD and concurrent atopic dermatitis.
Effective treatment with intravenous immunoglobulin for Henoch-Schönlein purpura with refractory gastrointestinal symptoms in an adolescent: A CARE-compliant case report.
Medicine (Baltimore)
November 2024
Department of Gastroenterology, The Second Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine, Guangzhou, China.
Rationale: This article presents a complex case of refractory Henoch-Schönlein purpura (HSP), initially manifesting with complex gastrointestinal (GI) symptoms, and discusses diagnostic and therapeutic challenges encountered. It aims to enhance understanding of the disease and provide evidence for the potential efficacy of intravenous immunoglobulin (IVIG) treatment in this condition.
Patient Concerns: A 16-year-old male patient presented with persistent abdominal pain, nausea, vomiting, and constipation for 8 days, leading to hospital admission.
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