Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.cgh.2014.07.006 | DOI Listing |
BMC Chem
January 2025
Department of Pharmacy, Birla Institute of Technology and Science Pilani, Pilani Campus, Vidya Vihar, Pilani, Rajasthan, 333 031, India.
A large set of antimalarial molecules (N ~ 15k) was employed from ChEMBL to build a robust random forest (RF) model for the prediction of antiplasmodial activity. Rather than depending on high throughput screening (HTS) data, molecules tested at multiple doses against blood stages of Plasmodium falciparum were used for model development. The open-access and code-free KNIME platform was used to develop a workflow to train the model on 80% of data (N ~ 12k).
View Article and Find Full Text PDFBMC Sports Sci Med Rehabil
January 2025
Department of Physiotherapy, School of Rehabilitation, Tehran University of Medical Science, Enghelab St, Pich-e-Shemiran, Tehran, Iran.
Background: Chronic ankle instability (CAI) is characterized by recurrent sprains and persistent symptoms, which impair postural control. This study evaluates the diagnostic utility of various linear and nonlinear postural stability measures in distinguishing individuals with CAI from healthy controls.
Methods: Postural stability was assessed in 24 participants (12 with CAI and 12 healthy controls) using a force platform under four conditions: hard surface with eyes open, hard surface with eyes closed, soft surface with eyes open, and soft surface with eyes closed.
BioData Min
January 2025
Department of Statistics, College of Science, Bahir Dar University, P.O. Box 79, Bahir Dar, Ethiopia.
Background: This study employs a LSTM-FC neural networks to address the critical public health issue of child undernutrition in Ethiopia. By employing this method, the study aims classify children's nutritional status and predict transitions between different undernutrition states over time. This analysis is based on longitudinal data extracted from the Young Lives cohort study, which tracked 1,997 Ethiopian children across five survey rounds conducted from 2002 to 2016.
View Article and Find Full Text PDFBMC Oral Health
January 2025
Department of Anaesthesiology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410008, China.
Background: Postoperative fever (POF) is a common occurrence in patients undergoing major surgery, presenting challenges and burdens for both patients and surgeons yet. This study endeavors to examine the incidence, identify risk factors, and establish a machine learning-based predictive model for POF following surgery of oral cancer.
Methods: A total of seven hundred and twenty-seven consecutive patients undergoing radical resection of oral cancer were retrospectively investigated.
Arthritis Res Ther
January 2025
Rheumazentrum Ruhrgebiet Herne, Ruhr University Bochum, Herne, Germany.
Background: Optical spectral transmission (OST) is a modern diagnostic method capable of quantifying inflammation in the finger and wrist joints of arthritis patients by assessing the blood-specific absorption of light transmitted through a tissue. The diagnostic performance of this modality has not been adequately examined and data regarding OST associations with magnetic resonance imaging (MRI) are limited. Aim of this study was therefore to investigate the performance of OST in assessing joint inflammation as compared to MRI in patients with inflammatory arthritis (IA).
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!